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Concept

Sciatica

Related publications (10)

Lumbar discectomy with annulus fibrosus closure: A retrospective series of 53 consecutive patients

Constantin Tuleasca

Introduction. - Lumbar disc herniation is most common degenerative alteration of the spine. Whenever surgical therapy proves to be necessary, recurrent disc herniation is most frequent concern. Here, primary aim was to determine the percentage of patients ...

2022

Clinical implementation of accelerated T-2 mapping: Quantitative magnetic resonance imaging as a biomarker for annular tear and lumbar disc herniation

Tobias Kober, Tom Hilbert

Objectives This study evaluates GRAPPATINI, an accelerated T-2 mapping sequence combining undersampling and model-based reconstruction to facilitate the clinical implementation of T-2 mapping of the lumbar intervertebral disc. Methods Fifty-eight individua ...

SPRINGER2021

Tailoring swelling to control softening mechanisms during cyclic loading of PEG/cellulose hydrogel composites

Dominique Pioletti, Pierre-Etienne Bourban, Baris Çaglar, Azadeh Khoushabi, Céline Samira Wyss

One of the novel approaches for discogenic lower back pain treatment is to permanently replace the core of the intervertebral disc, so-called Nucleus Pulposus, through minimally invasive surgery. Recently, we have proposed Poly(Ethylene Glycol) Dimethacryl ...

2018

Surgical probe and implant development for nucleus pulposus replacements

Andreas Schmocker

Intervertebral disc degeneration is a major reason why we experience low back pain. Intervertebral discs are located in-between the vertebrae of the spine. They act, among other, as shock absorbers by distributing the mechanical load applied to the spine w ...

EPFL2016

Chronic multichannel neural recordings from soft regenerative microchannel electrodes during gait

Silvestro Micera, Stéphanie Lacour, Marco Capogrosso, Sophie Marie Marthe Wurth, Katherine Marie Musick, Jacopo Rigosa

Reliably interfacing a nerve with an electrode array is one of the approaches to restore motor and sensory functions after an injury to the peripheral nerve. Accomplishing this with current technologies is challenging as the electrode-neuron interface ofte ...

Nature Publishing Group2015

Multi-Scale Modeling Of Photopolymerization For Medical Hydrogel-Implant Design

Jan-Anders Edvin Maansson, Dominique Pioletti, Pierre-Etienne Bourban, Salma Farahi, Andreas Schmocker, Azadeh Khoushabi

We report on the modeling of a photopolymerizable hydrogel and its application as a replacement of the interior of the intervertebral disc (so called Nucleus Pulposus). The hydrogel is initially injected in its liquid form and then photopolymerized via a s ...

Spie-Int Soc Optical Engineering2013

PDMS Microchannel Regenerative Peripheral Nerve Interface

Stéphanie Lacour, Katherine Marie Musick

We have fabricated a soft silicone structure to support the regeneration of a sciatic nerve. The device consists of 70 parallel (120 x 110 mu m(2)) channels through which axons extend and then reconnect to the muscles on the other side of the device. Throu ...

Ieee2013

Damping properties of the nucleus pulposus

Dominique Pioletti, Arne Christian Vogel

Background: The nucleus pulposus is extremely deformable and it is not uncommon to observe strain amplitudes as large as 12.5% in physiological loading conditions. It has been shown that the nucleus pulposus contributes to the damping properties of the int ...

Elsevier2012

Thermomechanical Hysteresis of Biological and Synthetic Hydrogels : Theory, Characterisation, and Development of a Novel Deformation Calorimeter

Arne Christian Vogel

The nucleus pulposus of the intervertebral disc is a gelatinous viscous hydrogel that has an essential role in the mechanics of the intervertebral disc joint. The viscoelastic properties of the nucleus pulposus significantly change in the course of time an ...

EPFL2011

Biocomposite Hydrogels with Carboxymethylated, Nanofibrillated Cellulose Powder for Replacement of the Nucleus Pulposus

Jan-Anders Edvin Maansson, Pierre-Etienne Bourban, Ana Borges de Couraça, Fabien Duc

Biocomposite hydrogels with carboxymethylated, nanofibrillated cellulose (c-NFC) powder were prepared by UV polymerization of N-vinyl-2-pyrrolidone with Tween 20 trimethacrylate as a cross-linking agent for replacement of the native, human nucleus pulposus ...

American Chemical Society2011