Giovanni De MicheliExpertise
Design technologies for integrated systems on silicon, such as synthesis, hw/sw codesign and low-power design, as well as systems on heterogeneous platforms including electrical and biological components.
Scientific Director of EcoCloud Center at EPFL
Directing activities towards creating sustainable computation including AI.Designing energy-savvy data centers and edge devices.
More information
Please read http://si2.epfl.ch/~demichel/
Giovanni De Micheli is a research scientist in electronics and Mohammad Amin ShokrollahiAmin Shokrollahi has worked on a variety of topics, including coding theory, computational number theory and algebra, and computational/algebraic complexity theory. He is best known for his work on iterative decoding algorithms of graph based codes, an area in which he holds a number of granted and pending patents. He is the co-inventor of Tornado codes, and the inventor of Raptor codes. His codes have been standardized and successfully deployed in practical areas dealing with data transmission over lossy networks.
Prior to joining EPFL, Amin Shokrollahi has held positions as the chief scientist of Digital Fountain, member of the technical staff at Bell Laboratories, senior researcher at the International Computer Science Insitute in Berkeley, and assistant professor at the department of computer science of the university of Bonn. He is a Fellow of the IEEE, and he was awarded the Best Paper Award of the IEEE IT Society in 2002 for his work on iterative decoding of LDPC code, the IEEE Eric Sumner Award in 2007 for the development of Fountain Codes, and the joint Communication Society/Information Theory Society best paper award of 2007 for his paper on Raptor Codes.
Paolo GermanoFORMATION
Mars 1990 : Engagement au Laboratoire d'électromécanique et de machines électriques (LEME), devenu entre temps le laboratoire d'actionneurs intégrés (LAI), comme assistant puis comme fonctionnaire scientifique.
Janvier 1990 : Diplôme d'ingénieur EPF en microtechnique.
Juillet 1985 : Maturité de type scientifique.
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- EXPERIENCES ET DOMAINES DE COMPETENCES
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Modélisation et simulation de l'alimentation des moteurs de l'avion Solar Impulse sur la base des résultats de la modélisation par éléments finis (FEM) de la structure magnétique Développement du banc de mesure (mécanique et software) du moteur Solar Impulse (dès mars 2004);
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Dans le cadre d'un Projet CTI en collaboration avec l'entreprise Medtronic (Projet ColoStim), développement d'un appareil de traitement de la constipation consistant en des électrodes implantées le long du colon et alimentées par induction, à haute fréquence, à l'aide d'une bobine primaire placée autour du thorax du patient (janvier 2006 - mars 2007);
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Développement du modèle équivalent d'une montre à glace tactile et analyse de l'effet des décharges électrostatiques sur cette montre. Projet CTI en collaboration avec l'entreprise ETA-Swatch Group (avril 2003 à octobre 2004);
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Développement d'un système de transfert d'énergie pour navettes automotrices de machines d'assemblage. Projet CTI en collaboration avec l'entreprise Montech AG (octobre 2001 à octobre 2002);
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Développement d'une installation de transfert d'énergie pour des wagonnets de transport de rouleaux pour l'industrie du papier avec l'entreprise Valmet AG (Groupe Metso Paper) (2001);
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Développement d'un banc de mesure pour actionneurs linéaires dans le cadre d'un mandat avec l'entreprise Sonceboz SA (mars 1998 - juillet 2000);
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Développement d'une installation de transfert d'énergie pour un convoyeur d'outils dans le cadre d'un mandat avec l'entreprise MCM SpA (Italie) (juillet 1998 avril 1999 et déc. 1999 avril 2000);
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Développement d'un banc de test pour vibreur électromécanique dans le cadre d'un mandat avec l'entreprise ASULAB SA à Marin (octobre décembre 1999);
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Développement et responsabilité d'une installation de démonstration d'un Système de transport automatique à transmission d'énergie par induction - Projet Serpentine 2 PSEL (déc. 1996 juin 1999);
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Développement d'un banc de mesure et d'analyse pour moteurs à courant continu dans le cadre d'un projet d'impulsion RAVEL (sept. 1995 - mars 1997);
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Développement d'un convertisseur de fréquence à résonance de 2,4 kW pour l'alimentation d'un transformateur sans fer dans le cadre du transfert d'énergie sans contacts Projet Serpentine PSEL (février 94 déc. 1995);
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Développement d'un banc de mesure pour moteurs pas à pas dans le cadre d'un mandat avec l'entreprise Sonceboz SA (mars 1992 nov. 1995);
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Développement d'un convertisseur direct de fréquence AC/AC de basse puissance dans le cadre du projet du cur artificiel Suisse (mars 1990 - mars 1992);
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Suivi d'une vingtaine de projets de semestre et de master EPFL;
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Divers projets de moindre envergure (alimentations, démonstrateurs, acquisitions de données, micro-informatique, circuits imprimés).
PUBLICATIONS
DOMAINE DU TRANSFERT D'ENERGIE PAR INDUCTION
M. Jufer, L. Cardoletti, B. Arnet, P. Germano, Ch. Koechli, N. Macabray, M. Perrottet, "Dispositif de transmission d'énergie électrique à un véhicule, sans contact, par induction - Projet PSEL N° 16 - Magnéto-glisseur", Rapport de synthèse 1995, EPFL-DE-LEME, Lausanne - Suisse, 18 octobre 1995;
M. Jufer, L. Cardoletti, P. Germano, B. Arnet, M. Perrottet, N. Macabrey, "Induction Contactless Energy Transmission System for an Electric Vehicle", ICEM96, International Conference on Electrical Machines, Vigo, Sept. 10-12, 1996, Vol II, pp. 343-347;
P. Germano, M. Jufer, "Contactless power transmission: Frequency tuning by a maximum power tracking method", EPE '97, 7th European Conference on power electronics and applications, Trondheim, Sept. 8-10, 1997, Vol IV, pp. 693-697;
M. Jufer, L. Cardoletti, P. Germano, B. Arnet, M. Perrottet, Swiss Federal Institute of Techno-logy, DE-LEME, 1015 Lausanne, Switzer-land, "Inductively powered automatic vehicles - Ser-pen-tine", EVS-15 '98, 15th International Electric Vehicle Symposium and Exhibition, Brussel, Belgium, Sept. 29 - Oct. 3, 1998, pp. 403-404;
P. Germano, Nicolas Macabrey, M. Jufer, Swiss Federal Institute of Technology, DE-LEME, 1015 Lausanne, Switzerland, "Contactless Power Transmission: Linear Positioning of the Moving Element", EPE '99, 8th European Conference on Power Electronics and Applications, Lausanne, 7-9 September, 1999, Art Nb 685;
P. Germano, M. Jufer, L. Cardoletti, B. Arnet, Ch. Koechli, N. Macabray, M. Perrottet, "Système de transport automatique à transmission d'énergie par induction. - Projet PSEL N° 115", Rapport final 1999, EPFL-DE-LEME, Lausanne - Suisse, 31 août 1999;
P. Germano, I. Stefanini, W. Montella, L. Cardoletti, Y. Perriard, "Système de transfert d'énergie pour navette de machines d'assemblage Projet CTI n° 5780.1 KTS", Rapport final, EPF Lausanne-LAI, Suisse, mars 2004;
I. Stefanini, P. Germano, L. Cardoletti, W. Montella, Y. Perriard, "Inductive Charge System for Assembly Plant Shuttles", CD-ROM, EPE 2003, Toulouse, (France), 2-4 Septembre 2003;
P. Germano, I. Stefanini, Y. Perrirad, "Stimulation colique pour le traitement des troubles de la motilité Projet ColoStim Projet CTI n° 7362.2 LSPP-LS", Rapport final, EPF Lausanne-LAI, Suisse, mai 2007.
DOMAINES DES BANCS DE MESURE - MESURES
P. Germano, "Système automatique de mesure", Rapport technique vol. I & II, EPF-Lausanne, 1995;
P. Germano, Ch. Kuert, "Banc de mesures automatisé pour entraînements électriques", Présentation et mode d'emploi, EPF-Lausanne, 1997;
P. Germano, Ch. Kuert, M. Jufer, Swiss Federal Institute of Technology, DE-LEME, 1015 Lausanne, Switzerland, "Automated test bench for electric drives: Modular layout of soft- and hardware", EPE '99, 8th European Conference on Power Electronics and Applications, Lausanne, 7-9 September, 1999, Art Nb 683;
Y. Perriard, P. Germano, I. Verettaz, "Banc de test pour vibreur électromécanique", Rapport technique, EPF-Lausanne, janvier 2000;
P. Germano, Ch. Kuert, M. Jufer, Swiss Federal Institute of Technology, DE-LEME, 1015 Lausanne, Switzerland, "DSP controlled automated Test Bench for linear Actuators Design and Choices", EPE 2001, 9th European Conference on Power Electronics and Applications, Graz, 27-29 August, 2001, Art Nb 709;
P. Germano, M. Crivii, D. Demarco, Y. Perriard, Swiss Federal Instutute of Technology, LAI, 1015 Lausanne, Switzerland & L. Paratte, R. Marquis, Service Unit RD, ETA SA (Swatch Group), 2540 Granges, Switzerland, "Analysis and Modeling of Electrostatic Discharge in a Tactile Glass Featured Watch", IAS 2004, 39th Annual Meeting, Seattle, WA, USA, October 3-7, 2004;
P. Germano, M. Crivii, D. Demarco, Y. Perriard, Swiss Federal Instutute of Technology, LAI, 1015 Lausanne, Switzerland & L. Paratte, R. Marquis, Service Unit RD, ETA SA (Swatch Group), 2540 Granges, Switzerland, "Analysis and Modeling of Electrostatic Discharge in a Tactile Glass Featured Watch", IEEE Transaction on Industry Applications, Volume 43, Issue 4, July-aug. 2007, Page(s): 1091-1098; Paolo IennePaolo Ienne has been a Professor at the EPFL since 2000 and heads the Processor Architecture Laboratory (LAP). Prior to that, he worked for the Semiconductors Group of Siemens AG, Munich, Germany (which later became Infineon Technologies AG) where he was at the head of the Embedded Memories unit in the Design Libraries division. His research interests include various aspects of computer and processor architecture, FPGAs and reconfigurable computing, electronic design automation, and computer arithmetic. Ienne was a recipient of Best Paper Awards at the 20th, 24th, and 28th ACM/SIGDA International Symposia on Field-Programmable Gate Arrays (FPGA), in 2012, 2016 and 2020, at the 19th and 30th International Conference on Field-Programmable Logic and Applications (FPL), in 2009 and 2020, at the International Conference on Compilers, Architectures, and Synthesis for Embedded Systems (CASES), in 2007, and at the 40th Design Automation Conference (DAC), in 2003; many other papers have been candidates to Best Paper Awards in prestigious venues. He has served as general, programme, and topic chair of renown international conferences, including organizing in Lausanne the 26th International Conference on Field-Programmable Logic and Applications (FPL) in 2016. He serves on the steering committee of the IEEE Symposium on Computer Arithmetic (ARITH) and of the International Conference on Field-Programmable Logic and Applications (FPL). Ienne has guest edited a number of special issues and special sections on various topics for IEEE and ACM journals. He is regularly member of program committees of international workshops and conferences in the areas of design automation, computer architecture, embedded systems, compilers, FPGAs, and asynchronous design. He has been an associate editor of ACM Transactions on Architecture and Code Optimization (TACO), since 2015, of ACM Computing Surveys (CSUR), since 2014, and of ACM Transactions on Design Automation of Electronic Systems (TODAES) from 2011 to 2016.
Maher KayalMaher Kayal received M.S. and Ph.D degrees in electrical engineering from the Ecole Polytechnique Fédérale de Lausanne (EPFL, Switzerland) in 1983 and 1989 respectively. He has been with the Electronics laboratories of the Ecole Polytechnique Fédérale de Lausanne (EPFL, Switzerland) since 1990, where he is currently a professor and director of the Energy Management and Sustainability" section. He has published many scientific papers, coauthor of three text books dedicated to mixed-mode CMOS design and he holds eleven patents. His technical contributions have been in the area of analog and Mixed-signal circuits design including highly linear and tunable sensors microsystems, signal processing and green energy management.
Prizes and Honors
Electronics Letters journal Premium Award 2013,
Outstanding Paper Award? IEEE Mixdes 2013
Basil Papadias paper Award, IEEE Powertech 2013
Best Paper Awards, Mixdes 2013
Best Paper Awards, ICCAS 2012
Outstanding Paper Award- IEEE Mixdes 2012.
Poland Section IEEE ED Chapter special award in 2011.
Credit Suisse Award for Best Teaching- 2009.
The William M. Portnoy Award at the Energy Conversion Congress and Exposition , California Sept 2009.
Best Paper Award - IEEE-Mixdes 2009.
High Quality Paper - IEEE Power Tech Conference June 2009.
Best Paper Award - IEEE-Mixdes 2007.
Best Paper Award - IEEE-TTTC International Conference on Automation, Quality and Testing, Robotics - 2006.
Best Application Specific Integrated Circuit at the International European Design and Test Conference ED&TC - 1997.
Ascom Award for the Best Work in Telecommunication Fields 1990.
Publications Books.
Books:
Methodology for the Digital Calibration of Analog Circuits and Systems, Marc Pastre & Maher Kayal. Springer Publisher- (ISBN 1-4020-4252-3)-2006.
Structured Analog CMOS Design, Danica Stefanovic & Maher Kayal. Springer Publisher-(ISBN 978-1-4020-8572-7)-2008.
Linear CMOS RF Amplifiers for Wireless Applications, Maher Kayal, Springer Publisher. (ISBN 978-90-481-9360-8)-2010.
Coeditor of Microelectronics Education Kluwer Academic Publishers. (ISBN 1-4020-2072-4). -2004.
Yves PerriardYves Perriard was born in Lausanne in 1965. He received the M. Sc. in Microengineering from the Swiss Federal Institute of Technology - Lausanne (EPFL) in 1989 and the Ph D. degree in 1992. Co-founder of Micro-Beam SA, he was CEO of this company involved in high precision electric drive. Senior lecturer from 1998 and professor since 2003, he is currently director of Laboratory of Integrated Actuators. His research interests are in the field of new actuator design and associated electronic devices. In 2009, he is appointed Vice-Director of the Microengineering Institute in Neuchâtel until 2011. In 2013 the Federal Council has named him the the CTI commission in Bern. In 2014 he is appointed guest professor at Zhejiang University in China. In 2017, the lab is granted by the Werner Siemens Foundation of an amount of 12 millions CHF in order to set up a new Center for Artificial Muscules. Since 2018, he is Expert with Innosuisse, the new Swiss Innovation Agency. http://scholar.google.com/citations?hl=fr&user=V2onuO8AAAAJ https://actu.epfl.ch/news/a-12-million-franc-donation-to-create-a-center-for/ Edoardo CharbonEdoardo Charbon (SM’00 F’17) received the Elektrotechnik Diploma from ETH Zurich, the M.S. from the University of California at San Diego, and the Ph.D. from the University of California at Berkeley in 1988, 1991, and 1995, respectively, all in electrical engineering and EECS. He has consulted with numerous organizations, including Bosch, X-Fab, Texas Instruments, Maxim, Sony, Agilent, and the Carlyle Group. He was with Cadence Design Systems from 1995 to 2000, where he was the architect of the company's initiative on information hiding for intellectual property protection. In 2000, he joined Canesta Inc., as the Chief Architect, where he led the development of wireless 3-D CMOS image sensors. Since 2002 he has been a member of the faculty of EPFL, where is a full professor since 2015. From 2008 to 2016 he was full professor and chair at the Delft University of Technology, where he spearheaded the university's effort on cryogenic electronics for quantum computing as part of QuTech. He has been the driving force behind the creation of deep-submicron CMOS SPAD technology, which is mass-produced since 2015 and is present in smartphones, telemeters, proximity sensors, and medical diagnostics tools. His interests span from 3-D vision, LiDAR, FLIM, FCS, NIROT to super-resolution microscopy, time-resolved Raman spectroscopy, and cryo-CMOS circuits and systems for quantum computing. He has authored or co-authored over 400 papers and two books, and he holds 23 patents. Dr. Charbon is a distinguished visiting scholar of the W. M. Keck Institute for Space at Caltech, a fellow of the Kavli Institute of Nanoscience Delft, a distinguished lecturer of the IEEE Photonics Society, and a fellow of the IEEE.
Sanidhya KashyapSanidhya Kashyap is a systems researcher and an assistant professor at the EPFL School of Computer and Communication Sciences (IC). His research focuses on designing systems software that are performant and robust for heterogeneous hardware. He is broadly interested in the area of systems with a particular focus on operating systems, databases, concurrency, scheduling, networks, data analytics, and software testing (fuzzing).
David Atienza AlonsoDavid Atienza Alonso is an associate professor of EE and director of the Embedded Systems Laboratory (ESL) at EPFL, Switzerland. He received his MSc and PhD degrees in computer science and engineering from UCM, Spain, and IMEC, Belgium, in 2001 and 2005, respectively. His research interests include system-level design methodologies for multi-processor system-on-chip (MPSoC) servers and edge AI architectures. Dr. Atienza has co-authored more than 350 papers, one book, and 12 patents in these previous areas. He has also received several recognitions and award, among them, the ICCAD 10-Year Retrospective Most Influential Paper Award in 2020, Design Automation Conference (DAC) Under-40 Innovators Award in 2018, the IEEE TCCPS Mid-Career Award in 2018, an ERC Consolidator Grant in 2016, the IEEE CEDA Early Career Award in 2013, the ACM SIGDA Outstanding New Faculty Award in 2012, and a Faculty Award from Sun Labs at Oracle in 2011. He has also earned two best paper awards at the VLSI-SoC 2009 and CST-HPCS 2012 conference, and five best paper award nominations at the DAC 2013, DATE 2013, WEHA-HPCS 2010, ICCAD 2006, and DAC 2004 conferences. He serves or has served as associate editor of IEEE Trans. on Computers (TC), IEEE Design & Test of Computers (D&T), IEEE Trans. on CAD (T-CAD), IEEE Transactions on Sustainable Computing (T-SUSC), and Elsevier Integration. He was the Technical Program Chair of DATE 2015 and General Chair of DATE 2017. He served as President of IEEE CEDA in the period 2018-2019 and was GOLD member of the Board of Governors of IEEE CASS from 2010 to 2012. He is a Distinguished Member of ACM and an IEEE Fellow.
Guido HaefeliTeaching & PhD PhD Students Federico Ronchetti, Gauri Napoletano Past EPFL PhD Students as codirector Axel Kuonen, Olivier Göran Girard, Carina Trippl Courses Particle detection PHYS-440 The course will cover the physics of particle detectors. It will introduce the experimental techniques used in nuclear and particle physics. The lecture includes the interaction of particles with matter, scintillators, gas detectors, silicon detectors, detectors for particle ID and photo-detectors.
Edouard BugnionEdouard Bugnion joined EPFL in 2012, where his focus is on datacenter systems. His areas of interest include operating systems, datacenter infrastructure (systems and networking), and computer architecture. Before joining EPFL, Edouard spent 18 years in the US, where he studied at Stanford and co-founded two startups: VMware and Nuova Systems (acquired by Cisco). At VMware from 1998 until 2005, he played many roles including CTO. At Nuova/Cisco from 2005 until 2011, he helped build the core engineering team and became the VP/CTO of Ciscos Server, Access, and Virtualization Technology Group, a group that brought to market Ciscos Unified Computing System (UCS) platform for virtualized datacenters. Prof. Bugnion is a Fellow of the ACM. Together with his colleagues, he received the ACM Software System Award for VMware 1.0 in 2009. His paper Disco: Running Commodity Operating Systems on Scalable Multiprocessors" received a Best Paper Award at SOSP '97 and was entered into the ACM SIGOPS Hall of Fame Award in 2008. At EPFL, he received the OSDI 2014 Best Paper Award for his work on the IX dataplane operating system
Babak FalsafiBabak is a Professor in the School of Computer and Communication Sciences and the founding director of the EcoCloud, an industrial/academic consortium at EPFL investigating scalable data-centric technologies. He has made numerous contributions to computer system design and evaluation including a scalable multiprocessor architecture which was prototyped by Sun Microsystems (now Oracle), snoop filters and memory streaming technologies that are incorporated into IBM BlueGene/P and Q and ARM cores, and computer system performance evaluation methodologies that have been in use by AMD, HP and Google PerKit . He has shown that hardware memory consistency models are neither necessary (in the 90's) nor sufficient (a decade later) to achieve high performance in multiprocessor systems. These results eventually led to fence speculation in modern microprocessors. His latest work on workload-optimized server processors laid the foundation for the first generation of Cavium ARM server CPUs, ThunderX. He is a recipient of an NSF CAREER award, IBM Faculty Partnership Awards, and an Alfred P. Sloan Research Fellowship. He is a fellow of IEEE and ACM.
Henry MarkramHenry Markram started a dual scientific and medical career at the University of Cape Town, in South Africa. His scientific work in the 80s revealed the polymodal receptive fields of pontomedullary reticular formation neurons in vivo and how acetylcholine re-organized these sensory maps.
He moved to Israel in 1988 and obtained his PhD at the Weizmann Institute where he discovered a link between acetylcholine and memory mechanisms by being the first to show that acetylcholine modulates the NMDA receptor in vitro studies, and thereby gates which synapses can undergo synaptic plasticity. He was also the first to characterize the electrical and anatomical properties of the cholinergic neurons in the medial septum diagonal band.
He carried out a first postdoctoral study as a Fulbright Scholar at the NIH, on the biophysics of ion channels on synaptic vesicles using sub-fractionation methods to isolate synaptic vesicles and patch-clamp recordings to characterize the ion channels. He carried out a second postdoctoral study at the Max Planck Institute, as a Minerva Fellow, where he discovered that individual action potentials propagating back into dendrites also cause pulsed influx of Ca2 into the dendrites and found that sub-threshold activity could also activated a low threshold Ca2 channel. He developed a model to show how different types of electrical activities can divert Ca2 to activate different intracellular targets depending on the speed of Ca2 influx an insight that helps explain how Ca2 acts as a universal second messenger. His most well known discovery is that of the millisecond watershed to judge the relevance of communication between neurons marked by the back-propagating action potential. This phenomenon is now called Spike Timing Dependent Plasticity (STDP), which many laboratories around the world have subsequently found in multiple brain regions and many theoreticians have incorporated as a learning rule. At the Max-Planck he also started exploring the micro-anatomical and physiological principles of the different neurons of the neocortex and of the mono-synaptic connections that they form - the first step towards a systematic reverse engineering of the neocortical microcircuitry to derive the blue prints of the cortical column in a manner that would allow computer model reconstruction.
He received a tenure track position at the Weizmann Institute where he continued the reverse engineering studies and also discovered a number of core principles of the structural and functional organization such as differential signaling onto different neurons, models of dynamic synapses with Misha Tsodyks, the computational functions of dynamic synapses, and how GABAergic neurons map onto interneurons and pyramidal neurons. A major contribution during this period was his discovery of Redistribution of Synaptic Efficacy (RSE), where he showed that co-activation of neurons does not only alter synaptic strength, but also the dynamics of transmission. At the Weizmann, he also found the tabula rasa principle which governs the random structural connectivity between pyramidal neurons and a non-random functional connectivity due to target selection. Markram also developed a novel computation framework with Wolfgang Maass to account for the impact of multiple time constants in neurons and synapses on information processing called liquid computing or high entropy computing.
In 2002, he was appointed Full professor at the EPFL where he founded and directed the Brain Mind Institute. During this time Markram continued his reverse engineering approaches and developed a series of new technologies to allow large-scale multi-neuron patch-clamp studies. Markrams lab discovered a novel microcircuit plasticity phenomenon where connections are formed and eliminated in a Darwinian manner as apposed to where synapses are strengthening or weakened as found for LTP. This was the first demonstration that neural circuits are constantly being re-wired and excitation can boost the rate of re-wiring.
At the EPFL he also completed the much of the reverse engineering studies on the neocortical microcircuitry, revealing deeper insight into the circuit design and built databases of the blue-print of the cortical column. In 2005 he used these databases to launched the Blue Brain Project. The BBP used IBMs most advanced supercomputers to reconstruct a detailed computer model of the neocortical column composed of 10000 neurons, more than 340 different types of neurons distributed according to a layer-based recipe of composition and interconnected with 30 million synapses (6 different types) according to synaptic mapping recipes. The Blue Brain team built dozens of applications that now allow automated reconstruction, simulation, visualization, analysis and calibration of detailed microcircuits. This Proof of Concept completed, Markrams lab has now set the agenda towards whole brain and molecular modeling.
With an in depth understanding of the neocortical microcircuit, Markram set a path to determine how the neocortex changes in Autism. He found hyper-reactivity due to hyper-connectivity in the circuitry and hyper-plasticity due to hyper-NMDA expression. Similar findings in the Amygdala together with behavioral evidence that the animal model of autism expressed hyper-fear led to the novel theory of Autism called the Intense World Syndrome proposed by Henry and Kamila Markram. The Intense World Syndrome claims that the brain of an Autist is hyper-sensitive and hyper-plastic which renders the world painfully intense and the brain overly autonomous. The theory is acquiring rapid recognition and many new studies have extended the findings to other brain regions and to other models of autism.
Markram aims to eventually build detailed computer models of brains of mammals to pioneer simulation-based research in the neuroscience which could serve to aggregate, integrate, unify and validate our knowledge of the brain and to use such a facility as a new tool to explore the emergence of intelligence and higher cognitive functions in the brain, and explore hypotheses of diseases as well as treatments.
