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Concept

Serum iron

Related publications (5)

Establishment of Reference Intervals of Blood Parameters Among the Healthy Afghan Population

Najia Sherzay

Purpose: This study was designed and conducted to validate the reference values of hematological parameters for healthy adult male and female residents of Kabul city, Afghanistan. Methodology: In this cross-sectional study, the samples were collected accor ...

Dove Medical Press Ltd2024

Iron status influences non-alcoholic fatty liver disease in obesity through the gut microbiome

Xavier Fernandez-Real Girona

Background: The gut microbiome and iron status are known to play a role in the pathophysiology of nonalcoholic fatty liver disease (NAFLD), although their complex interaction remains unclear. Results: Here, we applied an integrative systems medicine approa ...

2021

Intestinal ferritin H is required for an accurate control of iron absorption

Lukas Kühn

To maintain appropriate body iron levels, iron absorption by the proximal duodenum is thought to be controlled by hepcidin, a polypeptide secreted by hepatocytes in response to high serum iron. Hepcidin limits basolateral iron efflux from the duodenal epit ...

Cell Press2010

Conditional deletion of ferritin H in mice induces loss of iron storage and liver damage

Friedrich Beermann, Lukas Kühn

Ferritin plays a central role in iron metabolism by acting both as iron storage and detoxifying protein. We have generated a ferritin H allele with loxP sites and studied the conditional ferritin H deletion in adult mice. Ten days after Mx-Cre induced dele ...

2009

A mass spectrometric and molecular modelling study of cisplatin binding to transferrin

Paul Joseph Dyson, Claire Samantha Allardyce

A combination of mass spectrometry, UV/Vis spectroscopy and molecular modelling techniques hove been used to characterise the interaction of cisplatin with human serum transferrin (Tf). Mass spectrometry indicates that cisplatin binds to the hydroxy functi ...

2005