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Related publications (31)

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Fourier modeling of the BOLD response to a breath-hold task: Optimization and reproducibility

Patricia Figueiredo, João Pedro Forjaco Jorge

Cerebrovascular reactivity (CVR) reflects the capacity of blood vessels to adjust their caliber in order to maintain a steady supply of brain perfusion, and it may provide a sensitive disease biomarker. Measurement of the blood oxygen level dependent (BOLD ...

Elsevier2016

Total-activation regularized deconvolution of resting-state fMRI leads to reproducible networks with spatial overlap

Dimitri Nestor Alice Van De Ville, Fikret Isik Karahanoglu

Spontaneous activations in resting-state fMRI have been shown to corroborate recurrent intrinsic functional networks. Recent studies have explored integration of brain function in terms of spatially overlapping networks. We have proposed a method to recove ...

IEEE2016

Imaging of prolonged BOLD response in the somatosensory cortex of the rat

João Miguel das Neves Duarte, Rolf Gruetter, Nathalie Just, Sarah Catherine Sonnay

Blood oxygenation level-dependent (BOLD) functional MRI is a widely employed methodology in experimental and clinical neuroscience, although its nature is not fully understood. To gain insights into BOLD mechanisms and take advantage of the new functional ...

Wiley-Blackwell2015

Resting-State Temporal Synchronization Networks Emerge from Connectivity Topology and Heterogeneity

Patric Hagmann

Spatial patterns of coherent activity across different brain areas have been identified during the resting-state fluctuations of the brain. However, recent studies indicate that resting-state activity is not stationary, but shows complex temporal dynamics. ...

Public Library Science2015

Neuroenergetic Response to Prolonged Cerebral Glucose Depletion after Severe Brain Injury and the Role of Lactate

Pierre Magistretti, Jocelyne Bloch

Lactate may represent a supplemental fuel for the brain. We examined cerebral lactate metabolism during prolonged brain glucose depletion (GD) in acute brain injury (ABI) patients monitored with cerebral microdialysis (CMD). Sixty episodes of GD (defined a ...

Mary Ann Liebert2015

Transient brain activity disentangles fMRI resting-state dynamics in terms of spatially and temporally overlapping networks

Dimitri Nestor Alice Van De Ville, Fikret Isik Karahanoglu

Dynamics of resting-state functional magnetic resonance imaging (fMRI) provide a new window onto the organizational principles of brain function. Using state-of-the-art signal processing techniques, we extract innovation-driven co-activation patterns (iCAP ...

Nature Publishing Group2015

On spurious and real fluctuations of dynamic functional connectivity during rest

Dimitri Nestor Alice Van De Ville, Nora Leonardi

Functional brain networks reconfigure spontaneously during rest. Such network dynamics can be studied by dynamic functional connectivity (dynFC); i.e., sliding-window correlations between regional brain activity. Key parameters-such as window length and cu ...

Elsevier2015

Improving tumor heterogeneity MRI assessment with histograms

Nathalie Just

By definition, tumours are heterogeneous. They are defined by marked differences in cells, microenvironmental factors (oxygenation levels, pH, VEGF, VPF and TGF-α) metabolism, vasculature, structure and function that in turn translate into heterogeneous dr ...

Nature Publishing Group2014

Superior GRAPPA reconstruction with reduced g-factor noise using 2D CAIPIRINHA for 3D EPI

Rolf Gruetter, José Pedro Rebelo Ferreira Marques, Daniel Gallichan, Mayur Narsude

Efficient GRAPPA or SENSE reconstruction is largely dependent on coil geometry in the direction in which phase encoding steps reduction is performed during partially parallel acquisition. In this study we demonstrate the ability to perform a 2D CAIPIRINHA ...

2013

Digit somatotopy in the human cerebellum: A 7T fMRI study

Rolf Gruetter, Olaf Blanke, Wietske Van der Zwaag, José Pedro Rebelo Ferreira Marques, Roberto Martuzzi

The representation of the human body in the human cerebellum is still relatively unknown, compared to the well-studied homunculus in the primary somatosensory cortex. The investigation of the body representation in the cerebellum and its somatotopic organi ...

Academic Press Inc Elsevier Science2013

Sparsity-Promoting Spatiotemporal Regularization for Data Mining in Functional Magnetic Resonance Imaging

Fikret Isik Karahanoglu

Magnetic resonance imaging (MRI) has opened unprecedented avenues to observe the human brain non-invasively. In particular, for about two decades, functional MRI (fMRI) has enabled to monitor brain function using the blood-oxygen-level-dependent (BOLD) con ...

EPFL2013