Concept

Anastomosis

Related publications (13)

Future cardiovascular events prediction from invasive coronary angiography: A graph representation learning perspective

Improving risk stratification for coronary artery disease (CAD), the leading global cause of death, remains a daily challenge in clinical practice. This highlights the urgent need for innovative approaches to early prediction of future cardiovascular events from invasive coronary angiography (ICA), the gold standard imaging modality for CAD diagnosis. However, current methods, including clinical indices and data-driven deep learning models, fail to tackle this challenge. In this work, we propose AngioGraphC

Elsevier2026

Laue micro-diffraction and crystal plasticity finite element simulations to reveal a vein structure in fatigued Cu

Helena Van Swygenhoven, Nicolò Grilli, Ainara Irastorza Landa

The formation of a vein during cyclic shearing of a single copper crystal oriented for single slip can be followed in transmission Laue diffraction by analyzing the spatially resolved lattice rotation evolution. Because Laue transmission integrates the sig ...

2017

Connecting Ventricular Assist Devices to the Aorta: a Numerical Model

Alfio Quarteroni, Simone Deparis

Mechanical circulatory support, in particular ventricular assist devices (VAD), has been recently proposed as an alternative to transplantation in the treatment of terminal heart failure in the context of the lack of donors and raising number of patients on the waiting list. Although these systems have proved their efficiency through a rigorous patient selection, the complication rate remains high and experience shows that many of them are related to haemodynamic modifications due to VAD implantation. Furth

Springer2012

Segmentation and Grid Generation for Numerical Simulations of VAD Connections with Patientspecific Data

Alfio Quarteroni, Simone Deparis

Objectives: We are interested in the numerical simulation of the anastomotic region comprised between outflow canula of LVAD and the aorta. Segmentation, geometry reconstruction and grid generation from patient specific data remain an issue because of the variable quality of DICOM images, in particular CT-scan (e.g. metallic noise of the device, non-aortic contrast phase). We propose a general framework to overcome this problem and create suitable grids for numerical simulations. Methods: Preliminary treatm

2011

Pulse Wave Propagation in the Arterial Tree

Nikolaos Stergiopoulos

The beating heart creates blood pressure and flow pulsations that propagate as waves through the arterial tree that are reflected at transitions in arterial geometry and elasticity. Waves carry information about the matter in which they propagate. Therefore, modeling of arterial wave propagation extends our knowledge about the functioning of the cardiovascular system and provides a means to diagnose disorders and predict the outcome of medical interventions. In this review we focus on the physical and mathe

2011

Hysteresis Phenomena of a Macroscopic Fundamental Diagram in Freeway Networks

Observations of traffic pairs of flow vs. density or occupancy for individual locations in freeways or arterials are usually scattered about an underlying curve. Recent observations from empirical data in arterial networks showed that in some cases by aggregating the highly scattered plots of flow vs. density from individual loop detectors, the scatter almost disappears and well-defined macroscopic relations exist between space-mean network flow and network density. Despite these findings for the existence

Elsevier Science, Reg Sales Off, Customer Support Dept, 655 Ave Of The Americas, New York, Ny 10010 Usa2011

Vascular effects induced by anti-VEGF agents in the CAM model: Effect of the DMSO

Hubert van den Bergh, Georges Wagnières

The chicken embryo's chorioallantoic membrane (CAM) is widely used as an in vivo model to study the vascular effects induced by agents administrated topically or intravenously. Hence, in the vascular plexus of this respiratory membrane, angiogenic and anti-angiogenic agents, as well as phototoxic effects have been studied. The main goal of this study was to characterize the capillary network of the CAM after topical administration of dimethyl sulfoxid (DMSO), a frequently used solvent of lipophylic drugs, i

2009

On parallel computation of blood flow in human arterial network based on 1-D modelling

Alfio Quarteroni, Luca Formaggia

Parallel computation of blood flow in a 1D model of human arterial network has been carried out employing a Taylor Galerkin finite element method. Message passing interface libraries have been used on Origin 2000 SGI machine. A Greedy strategy for load-distribution has been devised and data-flow graphs necessary for parallelization have been generated. The performance of parallel implementation measured in terms of speedup and efficiency factors is found to be good. Further, the parallel code is used in sim

Springer-Verlag2003

Contribution to the heat integration of batch processes (with or without heat storage)

Pierre Krummenacher

This work addresses the indirect heat integration (i.e. resorting to intermediate heat storage) and the direct heat integration (i.e. heat exchanges between coexisting process streams) of batch processes. Tools and methods for the targeting of these two limiting cases of heat integration are proposed, and completed by the development and the application of an automatic design & optimization methodology using the Struggle genetic algorithm (GA). A brewery process is used to demonstrate the feasibility and th

EPFL2002

Total arterial inertance as the fourth element of the windkessel model

Nikolaos Stergiopoulos

In earlier studies we found that the three-element windkessel, although an almost perfect load for isolated heart studies, does not lead to accurate estimates of total arterial compliance. To overcome this problem, we introduce an inertial term in parallel with the characteristic impedance. In seven dogs we found that ascending aortic pressure could be predicted better from aortic flow by using the four-element windkessel than by using the three-element windkessel: the root-mean-square errors and the Akaike

1999

Physical basis of pressure transfer from periphery to aorta: a model-based study

Nikolaos Stergiopoulos

We propose a new method to derive aortic pressure from peripheral pressure and velocity by using a time domain approach. Peripheral pressure is separated into its forward and backward components, and these components are then shifted with a delay time, which is the ratio of wave speed and distance, and added again to reconstruct aortic pressure. We tested the method on a distributed model of the human systemic arterial tree. From carotid and brachial artery pressure and velocity, aortic systolic and diastol

1998

Determinants of stroke volume and systolic and diastolic aortic pressure

Nikolaos Stergiopoulos, Jean-Jacques Meister

We investigated how parameters describing the heart and the arterial system contribute to the systolic and diastolic pressures (Ps and Pd, respectively) and stroke volume (SV). We have described the heart by the varying-elastance model with six parameters and the systemic arterial tree by the three-element windkessel model, leading to a total of nine parameters. Application of dimensional analysis led to a total of six dimensionless parameters describing dimensionless Ps and Pd, i.e., pressures with respect

American Physiological Society1996

A new photopolymerizable blood vessel glue that seals human vessel anastomoses without augmenting thrombogenicity

A new nonbiologic photopolymerizable glue, polyethyleneglycol 400 diacrylate, was studied with respect to its mechanical and biochemical interaction with human blood vessels. Using the human placental artery model, we tested the ability of polyethyleneglycol 400 diacrylate to prevent leakage of blood at the site of vascular anastomoses, which are made porous by the presence of tissue gaps and suture puncture sites. Fibrin glue is known to augment local vessel thrombogenicity through the presence of the coag

1995

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Related publications (13)