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Concept

Interbreeding between archaic and modern humans

Related publications (27)

A model for brain life history evolution

Timm Faulwasser

Complex cognition and relatively large brains are distributed across various taxa, and many primarily verbal hypotheses exist to explain such diversity. Yet, mathematical approaches formalizing verbal hypotheses would help deepen the understanding of brain ...

Public Library Science2017

Adult human perception of distress in the cries of bonobo, chimpanzee, and human infants

Understanding the extent to which humans perceive the emotional state of animals has both theoretical and practical implications. While recent studies indicate that natural selection has led to some convergence of emotion coding among vertebrate species (i ...

Wiley2017

Red squirrels in the British Isles are infected with leprosy bacilli

Stewart Cole, Andrej Benjak, Charlotte Avanzi, Philippe Busso, Jérémie Piton

Leprosy, caused by infection with Mycobacterium leprae or the recently discovered Mycobacterium lepromatosis, was once endemic in humans in the British Isles. Red squirrels in Great Britain (Sciurus vulgaris) have increasingly been observed with leprosy-li ...

American Association for the Advancement of Science2016

Transposable Elements and Their KRAB-ZFP Controllers Regulate Gene Expression in Adult Tissues

Didier Trono, Priscilla Turelli, Sandra Eloise Kjeldsen, Julien Léonard Duc, Michaël Imbeault, Marco Cassano, Gabriela Ecco, Annamaria Kauzlaric, Andrea Coluccio

KRAB-containing zinc finger proteins (KRAB-ZFPs) are early embryonic controllers of transposable elements (TEs), which they repress with their cofactor KAP1 through histone and DNA methylation, a process thought to result in irreversible silencing. Using a ...

Cell Press - Elsevier2016

Reinforcement learning: the effect of environment

Michael Herzog, He Xu

Reinforcement learning is a type of supervised learning, where reward is sparse and delayed. For example in chess, a series of moves is made until a sparse reward (win, loss) is issued, which makes it impossible to evaluate the value of a single move. Stil ...

2016

Human-Specific Histone Methylation Signatures at Transcription Start Sites in Prefrontal Neurons

Jeffrey David Jensen

Cognitive abilities and disorders unique to humans are thought to result from adaptively driven changes in brain transcriptomes, but little is known about the role of cis-regulatory changes affecting transcription start sites (TSS). Here, we mapped in huma ...

Public Library Science2012

RAX and anophthalmia in humans: Evidence of brain anomalies

Purpose: To report the clinical and genetic study of two families of Egyptian origin with clinical anophthalmia. To further determine the role of the retina and anterior neural fold homeobox gene (RAX) in anophthalmia and associated cerebral malformations. ...

2012