Guido HaefeliTeaching & PhD PhD Students Federico Ronchetti, Gauri Napoletano Past EPFL PhD Students as codirector Axel Kuonen, Olivier Göran Girard, Carina Trippl Courses Particle detection PHYS-440 The course will cover the physics of particle detectors. It will introduce the experimental techniques used in nuclear and particle physics. The lecture includes the interaction of particles with matter, scintillators, gas detectors, silicon detectors, detectors for particle ID and photo-detectors.
Johan AuwerxJohan Auwerx is Professor at the École Polytechnique Fédérale in Lausanne, Switzerland, where he occupies the Nestle Chair in Energy Metabolism. Dr. Auwerx has been using molecular physiology and systems genetics to understand metabolism in health, aging and disease. Much of his work focused on understanding how diet, exercise and hormones control metabolism through changing the expression of genes by altering the activity of transcription factors and their associated cofactors. His work was instrumental for the development of agonists of nuclear receptors - a particular class of transcription factors - into drugs, which now are used to treat high blood lipid levels, fatty liver, and type 2 diabetes. Dr. Auwerx was amongst the first to recognize that transcriptional cofactors, which fine-tune the activity of transcription factors, act as energy sensors/effectors that influence metabolic homeostasis. His research validated these cofactors as novel targets to treat metabolic diseases, and spurred the clinical use of natural compounds, such as resveratrol, as modulators of these cofactor pathways.
Johan Auwerx was elected as a member of EMBO in 2003 and is the recipient of a dozen of international scientific prizes, including the Danone International Nutrition Award, the Oskar Minkowski Prize, and the Morgagni Gold Medal. His work is highly cited by his peers with a h-factor of over 100. He is an editorial board member of several journals, including Cell Metabolism, Molecular Systems Biology, The EMBO Journal, Journal of Cell Biology, Cell, and Science. Dr. Auwerx co-founded a handful of biotech companies, including Carex, PhytoDia, and most recently Mitobridge, and has served on several scientific advisory boards.
Dr. Auwerx received both his MD and PhD in Molecular Endocrinology at the Katholieke Universiteit in Leuven, Belgium. He was a post-doctoral research fellow in the Departments of Medicine and Genetics of the University of Washington in Seattle.
David Atienza AlonsoDavid Atienza Alonso is an associate professor of EE and director of the Embedded Systems Laboratory (ESL) at EPFL, Switzerland. He received his MSc and PhD degrees in computer science and engineering from UCM, Spain, and IMEC, Belgium, in 2001 and 2005, respectively. His research interests include system-level design methodologies for multi-processor system-on-chip (MPSoC) servers and edge AI architectures. Dr. Atienza has co-authored more than 350 papers, one book, and 12 patents in these previous areas. He has also received several recognitions and award, among them, the ICCAD 10-Year Retrospective Most Influential Paper Award in 2020, Design Automation Conference (DAC) Under-40 Innovators Award in 2018, the IEEE TCCPS Mid-Career Award in 2018, an ERC Consolidator Grant in 2016, the IEEE CEDA Early Career Award in 2013, the ACM SIGDA Outstanding New Faculty Award in 2012, and a Faculty Award from Sun Labs at Oracle in 2011. He has also earned two best paper awards at the VLSI-SoC 2009 and CST-HPCS 2012 conference, and five best paper award nominations at the DAC 2013, DATE 2013, WEHA-HPCS 2010, ICCAD 2006, and DAC 2004 conferences. He serves or has served as associate editor of IEEE Trans. on Computers (TC), IEEE Design & Test of Computers (D&T), IEEE Trans. on CAD (T-CAD), IEEE Transactions on Sustainable Computing (T-SUSC), and Elsevier Integration. He was the Technical Program Chair of DATE 2015 and General Chair of DATE 2017. He served as President of IEEE CEDA in the period 2018-2019 and was GOLD member of the Board of Governors of IEEE CASS from 2010 to 2012. He is a Distinguished Member of ACM and an IEEE Fellow.
Christoph KochExpertise
knows everything ;-)
Publications
My publications in Google ScholarMy publications in DBLPMy papers on EPFL's publications server (InfoScience)Prospective PhD students and postdocs please read this before contacting me.
Christoph Koch is a professor of Computer Science at EPFL, specializing in data management. Until 2010, he was an Associate Professor in the Department of Computer Science at Cornell University. Previously to this, from 2005 to 2007, he was an Associate Professor of Computer Scienc
Giovanna AmbrosiniCurrent Position Senior Scientist, School of Life Sciences, Bioinformatics Competence Center, école Polythechnique Fédérale de Lausanne, Lausanne.Senior bioinformatician and software engineer with proven experience working in higher education institutions. Solid experience in scientific computing and web design. Proficient in physics and computational genomics, with a focus on high-throughput genomic sequencing data analysis (ChIP-seq, ATAC-seq, RNA-seq, scRNA-seq, and exome sequencing) and other types of
Henry MarkramHenry Markram started a dual scientific and medical career at the University of Cape Town, in South Africa. His scientific work in the 80s revealed the polymodal receptive fields of pontomedullary reticular formation neurons in vivo and how acetylcholine re-organized these sensory maps.
He moved to Israel in 1988 and obtained his PhD at the Weizmann Institute where he discovered a link between acetylcholine and memory mechanisms by being the first to show that acetylcholine modulates the NMDA receptor in vitro studies, and thereby gates which synapses can undergo synaptic plasticity. He was also the first to characterize the electrical and anatomical properties of the cholinergic neurons in the medial septum diagonal band.
He carried out a first postdoctoral study as a Fulbright Scholar at the NIH, on the biophysics of ion channels on synaptic vesicles using sub-fractionation methods to isolate synaptic vesicles and patch-clamp recordings to characterize the ion channels. He carried out a second postdoctoral study at the Max Planck Institute, as a Minerva Fellow, where he discovered that individual action potentials propagating back into dendrites also cause pulsed influx of Ca2 into the dendrites and found that sub-threshold activity could also activated a low threshold Ca2 channel. He developed a model to show how different types of electrical activities can divert Ca2 to activate different intracellular targets depending on the speed of Ca2 influx an insight that helps explain how Ca2 acts as a universal second messenger. His most well known discovery is that of the millisecond watershed to judge the relevance of communication between neurons marked by the back-propagating action potential. This phenomenon is now called Spike Timing Dependent Plasticity (STDP), which many laboratories around the world have subsequently found in multiple brain regions and many theoreticians have incorporated as a learning rule. At the Max-Planck he also started exploring the micro-anatomical and physiological principles of the different neurons of the neocortex and of the mono-synaptic connections that they form - the first step towards a systematic reverse engineering of the neocortical microcircuitry to derive the blue prints of the cortical column in a manner that would allow computer model reconstruction.
He received a tenure track position at the Weizmann Institute where he continued the reverse engineering studies and also discovered a number of core principles of the structural and functional organization such as differential signaling onto different neurons, models of dynamic synapses with Misha Tsodyks, the computational functions of dynamic synapses, and how GABAergic neurons map onto interneurons and pyramidal neurons. A major contribution during this period was his discovery of Redistribution of Synaptic Efficacy (RSE), where he showed that co-activation of neurons does not only alter synaptic strength, but also the dynamics of transmission. At the Weizmann, he also found the tabula rasa principle which governs the random structural connectivity between pyramidal neurons and a non-random functional connectivity due to target selection. Markram also developed a novel computation framework with Wolfgang Maass to account for the impact of multiple time constants in neurons and synapses on information processing called liquid computing or high entropy computing.
In 2002, he was appointed Full professor at the EPFL where he founded and directed the Brain Mind Institute. During this time Markram continued his reverse engineering approaches and developed a series of new technologies to allow large-scale multi-neuron patch-clamp studies. Markrams lab discovered a novel microcircuit plasticity phenomenon where connections are formed and eliminated in a Darwinian manner as apposed to where synapses are strengthening or weakened as found for LTP. This was the first demonstration that neural circuits are constantly being re-wired and excitation can boost the rate of re-wiring.
At the EPFL he also completed the much of the reverse engineering studies on the neocortical microcircuitry, revealing deeper insight into the circuit design and built databases of the blue-print of the cortical column. In 2005 he used these databases to launched the Blue Brain Project. The BBP used IBMs most advanced supercomputers to reconstruct a detailed computer model of the neocortical column composed of 10000 neurons, more than 340 different types of neurons distributed according to a layer-based recipe of composition and interconnected with 30 million synapses (6 different types) according to synaptic mapping recipes. The Blue Brain team built dozens of applications that now allow automated reconstruction, simulation, visualization, analysis and calibration of detailed microcircuits. This Proof of Concept completed, Markrams lab has now set the agenda towards whole brain and molecular modeling.
With an in depth understanding of the neocortical microcircuit, Markram set a path to determine how the neocortex changes in Autism. He found hyper-reactivity due to hyper-connectivity in the circuitry and hyper-plasticity due to hyper-NMDA expression. Similar findings in the Amygdala together with behavioral evidence that the animal model of autism expressed hyper-fear led to the novel theory of Autism called the Intense World Syndrome proposed by Henry and Kamila Markram. The Intense World Syndrome claims that the brain of an Autist is hyper-sensitive and hyper-plastic which renders the world painfully intense and the brain overly autonomous. The theory is acquiring rapid recognition and many new studies have extended the findings to other brain regions and to other models of autism.
Markram aims to eventually build detailed computer models of brains of mammals to pioneer simulation-based research in the neuroscience which could serve to aggregate, integrate, unify and validate our knowledge of the brain and to use such a facility as a new tool to explore the emergence of intelligence and higher cognitive functions in the brain, and explore hypotheses of diseases as well as treatments.
Allison Marie BurnsTeaching & PhD Courses Bioinformatic Analysis of RNA-sequencing (Fall) BIO-693(a) Bioinformatic Analysis of RNA-sequencing (Spring) BIO-693(b) This course will take place at EPFL in June 2026, from 8th to 12th, in room AAC 137.It introduces the workflows and techniques that are used for the analysis of bulk and single-cell RNA-seq data. It empowers students to understand and analyze their own data.
Hervé BourlardTeaching & PhD Past EPFL PhD Students Astrid Hagen, Katrin Weber, Todd Stephenson, Jitendra Ajmera, Shajith Ikbal, Mathew Magimai Doss, Mohamed Faouzi Benzeghiba, Mark Barnard, Yann Rodriguez, Hemant Misra, Christos Dimitrakakis, Guillaume Lathoud, Alexei Pozdnoukhov, Agnès Just, Mikaela Keller, Norman Hoon Thian Poh, Dong Zhang, Florent Monay Michaud, Pedro Manuel Da Silva Quelhas, Kevin Smith, Silèye Oumar Ba, Bertrand Mesot, Hamed Ketabdar, David Grangier, Guillermo Aradilla, Jean-François Paiement, Nico
Martin VetterliMartin Vetterli was appointed president of EPFL by the Federal Council following a selection process conducted by the ETH Board, which unanimously nominated him.
Professor Vetterli was born on 4 October 1957 in Solothurn and received his elementary and secondary education in Neuchâtel Canton. He earned a Bachelor’s degree in electrical engineering from ETH Zurich (ETHZ) in 1981, a Master’s of Science degree from Stanford University in 1982, and a PhD from EPFL in 1986. Professor Vetterli taught at Columbia University as an assistant and then associate professor. He was subsequently named full professor in the Department of Electrical Engineering and Computer Sciences at the University of California at Berkeley before returning to EPFL as a full professor at the age of 38. He has also taught at ETHZ and Stanford University.
Professor Vetterli has earned numerous national and international awards for his research in electrical engineering, computer science and applied mathematics, including the National Latsis Prize in 1996. He is a fellow of both the Association for Computing Machinery and the Institute of Electrical and Electronics Engineers and a member the US National Academy of Engineering. He has published over 170 articles and three reference works.
Professor Vetterli’s work on the theory of wavelets, which are used in signal processing, is considered to be of major importance by his peers, and his areas of expertise, including image and video compression and self-organized communication systems, are central to the development of new information technologies. As the founding director of the National Centre of Competence in Research on Mobile Information and Communication Systems, Professor Vetterli is a staunch advocate of transdisciplinary research.
Professor Vetterli knows EPFL inside and out. An EPFL graduate himself, he began been teaching at the school in 1995, was vice president for International Affairs and then Institutional Affairs from 2004 to 2011, and served as dean of the School of Computer and Communication Sciences in 2011 and 2012. In addition to his role as president of the National Research Council of the Swiss National Science Foundation, a position he held from 2013 to 2016, he heads the EPFL’s Audiovisual Communications Laboratory (LCAV) since 1995.
Professor Vetterli has supported more than 60 students in Switzerland and the United States in their doctoral work and makes a point of following their highly successful careers, whether it is in the academic or business world.
He is the author of some 50 patents, some of which were the basis for start-ups coming out of his lab, such as Dartfish and Illusonic, while others were sold (e.g. Qualcomm) as successful examples of technology transfer. He actively encourages young researchers to market the results of their work.
Andy BushbyTeaching & PhD Courses CCMX Advanced Course - Instrumented Nanoindentation MSE-656 This course is intended for current nanoindentation users who want to gain the experience and knowledge required to extract useful data from challenging sample materials. It is also intended for users of conventional indentation methods who wish to add this approach to their portofolio of methods.
Nicholas X. RandallTeaching & PhD Courses CCMX Advanced Course - Instrumented Nanoindentation MSE-656 This course is intended for current nanoindentation users who want to gain the experience and knowledge required to extract useful data from challenging sample materials. It is also intended for users of conventional indentation methods who wish to add this approach to their portofolio of methods.
Edoardo ChiarottiTeaching & PhD Courses Data Science & Causal Inference for Sustainability MGT-499 This class explores key climate questions through data. Students will learn to collect, clean, and analyze data, apply causal methods using Python, and communicate insights clearly. With a focus on sustainability, the course builds skills to avoid pitfalls and draw meaningful conclusions.
Pierre DillenbourgA former teacher in elementary school, Pierre Dillenbourg graduated in educational science (University of Mons, Belgium). He started his research on learning technologies in 1984. In 1986, he has been on of the first in the world to apply machine learning to develop a self-improving teaching system. He obtained a PhD in computer science from the University of Lancaster (UK), in the domain of artificial intelligence applications for education. He has been assistant professor at the University of Geneva. He joined EPFL in 2002. He has been the director of Center for Research and Support on Learning and its Technologies, then academic director of Center for Digital Education, which implements the MOOC strategy of EPFL (over 2 million registrations). He is full professor in learning technologies in the School of Computer & Communication Sciences, where he is the head of the CHILI Lab: "Computer-Human Interaction for Learning & Instruction ». He is the director of the leading house DUAL-T, which develops technologies for dual vocational education systems (carpenters, florists,...). With EPFL colleagues, he launched in 2017 the Swiss EdTech Collider, an incubator with 80 start-ups in learning technologies. He (co-)-founded 4 start-ups, does consulting missions in the corporate world and joined the board of several companies or institutions. In 2018, he co-founded LEARN, the EPFL Center of Learning Sciences that brings together the local initiatives in educational innovation. He is a fellow of the International Society for Learning Sciences. He currently is the Associate Vice-President for Education at EPFL.
Nicolas Jean Philippe GuexTeaching & PhD Courses Bioinformatic Analysis of RNA-sequencing (Fall) BIO-693(a) Bioinformatic Analysis of RNA-sequencing (Spring) BIO-693(b) This course will take place at EPFL in June 2026, from 8th to 12th, in room AAC 137.It introduces the workflows and techniques that are used for the analysis of bulk and single-cell RNA-seq data. It empowers students to understand and analyze their own data. Methods: omics in biomedical research BIOENG-519 High-throughp
Giovanni De MicheliExpertise
Design technologies for integrated systems on silicon, such as synthesis, hw/sw codesign and low-power design, as well as systems on heterogeneous platforms including electrical and biological components.
Scientific Director of EcoCloud Center at EPFL
Directing activities towards creating sustainable computation including AI.Designing energy-savvy data centers and edge devices.
More information
Please read http://si2.epfl.ch/~demichel/
Giovanni De Micheli is a research scientist in electronics and