Francesco MondadaDr. Mondada received his M.Sc. in micro-engineering in 1991 and his Doctoral degree in 1997 at EPFL. During his thesis he co-founded the company K-Team, being both CEO and president of the company for about 5 years. He is one of the three main developers of the Khepera robot, considered as a standard in bio-inspired robotics and used by more than 1,000 universities and research centers worldwide. Fully back in research in 2000 and after a short period at CALTECH, he participated to the SWARM-BOTS project as the main developer of the s-bot robot platform, which was ranked on position 39 in the list of The 50 Best Robots Ever (fiction or real) by the Wired Journal in 2006. The SWARM-BOTS project was selected as FET-IST success story by the EU commission. He is author of more than 100 papers in the field of bio-inspired robotics and system level robot design. He is co-editor of several international conference proceedings. In November 2005 he received the EPFL Latsis University prize for his contributions to bio-inspired robotics. In 2011 he received the "Crédit Suisse Award for Best Teaching" from EPFL and in 2012 the "polysphère" award from the students as best teacher in the school of engineering. His interests include the development of innovative mechatronic solutions for mobile and modular robots, the creation of know-how for future embedded applications, and making robot platforms more accessible for education, research, and industrial development.
Henry MarkramHenry Markram started a dual scientific and medical career at the University of Cape Town, in South Africa. His scientific work in the 80s revealed the polymodal receptive fields of pontomedullary reticular formation neurons in vivo and how acetylcholine re-organized these sensory maps.
He moved to Israel in 1988 and obtained his PhD at the Weizmann Institute where he discovered a link between acetylcholine and memory mechanisms by being the first to show that acetylcholine modulates the NMDA receptor in vitro studies, and thereby gates which synapses can undergo synaptic plasticity. He was also the first to characterize the electrical and anatomical properties of the cholinergic neurons in the medial septum diagonal band.
He carried out a first postdoctoral study as a Fulbright Scholar at the NIH, on the biophysics of ion channels on synaptic vesicles using sub-fractionation methods to isolate synaptic vesicles and patch-clamp recordings to characterize the ion channels. He carried out a second postdoctoral study at the Max Planck Institute, as a Minerva Fellow, where he discovered that individual action potentials propagating back into dendrites also cause pulsed influx of Ca2 into the dendrites and found that sub-threshold activity could also activated a low threshold Ca2 channel. He developed a model to show how different types of electrical activities can divert Ca2 to activate different intracellular targets depending on the speed of Ca2 influx an insight that helps explain how Ca2 acts as a universal second messenger. His most well known discovery is that of the millisecond watershed to judge the relevance of communication between neurons marked by the back-propagating action potential. This phenomenon is now called Spike Timing Dependent Plasticity (STDP), which many laboratories around the world have subsequently found in multiple brain regions and many theoreticians have incorporated as a learning rule. At the Max-Planck he also started exploring the micro-anatomical and physiological principles of the different neurons of the neocortex and of the mono-synaptic connections that they form - the first step towards a systematic reverse engineering of the neocortical microcircuitry to derive the blue prints of the cortical column in a manner that would allow computer model reconstruction.
He received a tenure track position at the Weizmann Institute where he continued the reverse engineering studies and also discovered a number of core principles of the structural and functional organization such as differential signaling onto different neurons, models of dynamic synapses with Misha Tsodyks, the computational functions of dynamic synapses, and how GABAergic neurons map onto interneurons and pyramidal neurons. A major contribution during this period was his discovery of Redistribution of Synaptic Efficacy (RSE), where he showed that co-activation of neurons does not only alter synaptic strength, but also the dynamics of transmission. At the Weizmann, he also found the tabula rasa principle which governs the random structural connectivity between pyramidal neurons and a non-random functional connectivity due to target selection. Markram also developed a novel computation framework with Wolfgang Maass to account for the impact of multiple time constants in neurons and synapses on information processing called liquid computing or high entropy computing.
In 2002, he was appointed Full professor at the EPFL where he founded and directed the Brain Mind Institute. During this time Markram continued his reverse engineering approaches and developed a series of new technologies to allow large-scale multi-neuron patch-clamp studies. Markrams lab discovered a novel microcircuit plasticity phenomenon where connections are formed and eliminated in a Darwinian manner as apposed to where synapses are strengthening or weakened as found for LTP. This was the first demonstration that neural circuits are constantly being re-wired and excitation can boost the rate of re-wiring.
At the EPFL he also completed the much of the reverse engineering studies on the neocortical microcircuitry, revealing deeper insight into the circuit design and built databases of the blue-print of the cortical column. In 2005 he used these databases to launched the Blue Brain Project. The BBP used IBMs most advanced supercomputers to reconstruct a detailed computer model of the neocortical column composed of 10000 neurons, more than 340 different types of neurons distributed according to a layer-based recipe of composition and interconnected with 30 million synapses (6 different types) according to synaptic mapping recipes. The Blue Brain team built dozens of applications that now allow automated reconstruction, simulation, visualization, analysis and calibration of detailed microcircuits. This Proof of Concept completed, Markrams lab has now set the agenda towards whole brain and molecular modeling.
With an in depth understanding of the neocortical microcircuit, Markram set a path to determine how the neocortex changes in Autism. He found hyper-reactivity due to hyper-connectivity in the circuitry and hyper-plasticity due to hyper-NMDA expression. Similar findings in the Amygdala together with behavioral evidence that the animal model of autism expressed hyper-fear led to the novel theory of Autism called the Intense World Syndrome proposed by Henry and Kamila Markram. The Intense World Syndrome claims that the brain of an Autist is hyper-sensitive and hyper-plastic which renders the world painfully intense and the brain overly autonomous. The theory is acquiring rapid recognition and many new studies have extended the findings to other brain regions and to other models of autism.
Markram aims to eventually build detailed computer models of brains of mammals to pioneer simulation-based research in the neuroscience which could serve to aggregate, integrate, unify and validate our knowledge of the brain and to use such a facility as a new tool to explore the emergence of intelligence and higher cognitive functions in the brain, and explore hypotheses of diseases as well as treatments.
Michaël UnserExpertise
Image Processing, Medical Imaging, Biological Imaging, Wavelets, Splines, Multiresolution
Michael Unser is Full Professor with EPFL’s school of Engineering and the academic director of EPFL's Center for Imaging, Lausanne, Switzerland. His primary areas of investigation are signal processing, biomedical imaging and applied functional analysis. He is internationally recognized for his research contributions to sampling theory, wavelets, the use of splines for image processing, stochastic processes,
Dominique BonvinDominique Bonvin is Professor and Director of the Automatic Control Laboratory of EPFL. He received his Diploma in Chemical Engineering from ETH Zürich, and his Ph.D. degree from the University of California, Santa Barbara. He worked in the field of process control for the Sandoz Corporation in Basel and with the Systems Engineering Group of ETH Zürich. He joined the EPFL in 1989, where his current research interests include modeling, control and optimization of dynamic systems. He served as Director of the Automatic Control Laboratory for the periods 1993-97, 2003-2007 and again since 2012, Head of the Mechanical Engineering Department in 1995-97 and Dean of Bachelor and Master Studies at EPFL for the period 2004-2011.
André HodderTeaching & PhD PhD Students Lucien André Félicien Pierrejean Past EPFL PhD Students as codirector Simone Rametti Courses Actuators and Electromagnetic systems II MICRO-314 The students will be able to model, simulate and measure actuators and electrical motors Advanced lab in electrical energy systems EE-588 Pre-requisites required. The number of places is limited. Please register only after having obtained the teacher's agreement. The purpose of this teaching lab is to put
Roberto CastelloRoberto Castello is a senior scientist and group leader at the EPFL Laboratory of Solar Energy and Building Physics. Physicist by training, he has extensive experience in collecting, classifying and interpreting large datasets using advanced data mining techniques and statistical methods. He received his MSc (2007) in Particle Physics and PhD (2010) in Physics and Astrophysics from the University of Torino. He worked as a postdoctoral researcher at the Belgian National Research Fund (2011-2014) and at the CERN Experimental Physics Department (2015-2017) as a research fellow and data scientist. He is primary author of more than 20 peer-reviewed publications and he presented at major international conferences in the high energy physics domain.
In 2018 he joined the Solar Energy and Building Physics Laboratory (LESO-PB) to work on data mining and Machine Learning techniques for the built environment and renewable energy. His main research interests are: spatio-temporal modeling of renewable energy potential, energy consumption forecasting techniques, anomaly detection, and computer vision techniques for automated classification in the built environment.
He leads the group of Urban Data Mining, Intelligence and Simulation at LESO-PB and he is a member of the NRP75 Big Data project (HyEnergy) of the Swiss National Science Foundation. He is a member of the Swiss Competence Centre for Energy Research (SCCER) and deputy leader of the working group on Leveraging Ubiquitous Energy Data. He has served as a scientific committee member, workshop organizer and speaker at international conferences (ICAE 2020, Applied Machine Learning Days 2019 and 2020, CISBAT 2019 and 2021 and SDS2020).
Since 2017 he is member of the Geneva 2030 Ecosystem network, promoting the United Nations agenda towards the realization of the Sustainable Development Goals (SDGs).
Auke IjspeertAuke Ijspeert is a full professor at the EPFL, and head of the Biorobotics Laboratory (BioRob). He has a B.Sc./M.Sc. in physics from the EPFL (1995), and a PhD in artificial intelligence from the University of Edinburgh (1999). He carried out postdocs at IDSIA and EPFL, and at the University of Southern California (USC). He then became a research assistant professor at USC, and an external collaborator at ATR (Advanced Telecommunications Research institute) in Japan. In 2002, he came back to the EPFL as an SNF assistant professor. He was promoted to associate professor in October 2009 and to full professor in April 2016. His primary affiliation is with the Institute of Bioengineering, and secondary affiliation with the Institute of Mechanical Engineering. His research interests are at the intersection between robotics, computational neuroscience, nonlinear dynamical systems, and machine learning. He is interested in using numerical simulations and robots to get a better understanding of sensorimotor coordination in animals, and in using inspiration from biology to design novel types of robots and adaptive controllers. (see for instance Ijspeert et al Science 2007, Ijspeert Science 2014, and Nyakatura et al Nature 2019). He is also investigating how to assist people with limited mobility using exoskeletons and assistive furniture. He is regularly invited to give talks on these topics (e.g. TED talk given at TED Global Geneva, Dec 8 2015). With his colleagues, he has received paper awards at ICRA2002, CLAWAR2005, IEEE Humanoids 2007, IEEE ROMAN 2014, CLAWAR 2015, SAB2018, and CLAWAR 2019. He is an IEEE Fellow, member of the Board of Reviewing Editors of Science magazine, and associate editor for the IEEE Transactions on Medical Robotics and Bionics and for the International Journal of Humanoid Robotics. He has acted as an associate editor for the IEEE Transactions on Robotics (2009-2013) and for Soft Robotics (2018-2021). He was a guest editor for the Proceedings of IEEE, IEEE Transactions on Biomedical Engineering, Autonomous Robots, IEEE Robotics and Automation Magazine, and Biological Cybernetics. He has been the organizer of 7 international conferences (BioADIT2004, SAB2004, AMAM2005, BioADIT2006, LATSIS2006, SSRR2016, AMAM2019), and a program committee member of over 50 conferences.
Jérôme ChenalExpertise
Urban DesignUrban PlanningUrban ManagementPublic SpaceHousingDevelopment StudiesVisual Anthropology
Mission
Director of CEAT Director of Excellence in Africa Center Affiliate professor at UM6P
Teaching & PhD Past EPFL PhD Students Stéphanie Hasler, Rémi Jaligot, Armel Firmin Kemajou Mbianda, Martí Bosch Padrós, Andrea Salmi, Vitor Pessoa Colombo, Akuto Akpedze Konou, Rim Mrani Past EPFL PhD Students as codirector Marc Antoine Messer, Alexandre Rigal Courses Urban planning in the South PE
Philippe MüllhauptExpertise
Nonlinear Control (Geometry and Algebra)Classical DynamicsRoboticsStatistics
Mission
Provide rigorous technical and scientific training in nonlinear control, classical mechanics, and statistical theory
Current Work
Research and teaching in the fields of control theory, statistics, dynamical systems, and general mechanics.
Philippe Mullhaupt received his Diplôme d Education Ing�nieur | Electricit� 1993 – 1993 EPFL DEA | Automatique et Traitement du Signal 199
François MaréchalPh D. in engineering Chemical process engineer
Researcher and lecturer in the field of computer aided process and energy systems engineering.
Lecturer in the mechanical engineering, electrical engineering and environmental sciences engineering in EPFL.
I'm responsible for the Minor in Energy of EPFL and I'm involved in 3 projects of the Competence Center in Energy and Mobility (2nd generation biofuel, Wood SOFC, and gas turbine development with CO2 mitigation) in which i'm contributing to the energy conversion system design and optimisation.
Short summary of my scientific carrer
After a graduation in chemical engineering from the University of Liège, I have obtained a Ph. D. from the University of Liège in the LASSC laboratory of Prof. Kalitventzeff (former president of the European working party on computer aided process engineering). This laboratory was one of the pioneering laboratory in the field of Computer Aided Process Engineering.
In the group of Professor Kalitventzeff, I have worked on the development and the applications of data reconciliation, process modelling and optimisation techniques in the chemical process industry, my experience ranges from nuclear power stations to chemical plants. In the LASSC, I have been responsible from the developments in the field of rational use of energy in the industry. My first research topic has been the methodological development of process integration techniques, combining the use of pinch based methods and of mathematical programming: e.g. for the design of multiperiod heat exchanger networks or Mixed integer non linear programming techniques for the optimal management of utility systems. Fronted with applications in the industry, my work then mainly concentrated on the optimal integration of utility systems considering not only the energy requirements but the cost of the energy requirements and the energy conversion systems. I developed methods for analysing and integrating the utility system, the steam networks, combustion (including waste fuel), gas turbines or other advanced energy conversion systems (cogeneration, refrigeration and heat). The techniques applied uses operation research tools like mixed integer linear programming and exergy analysis. In order to evaluate the results of the utility integration, a new graphical method for representing the integration of the utility systems has been developed. By the use of MILP techniques, the method developed for the utility integration has been extended to handled site scale problems, to incorporate environmental constraints and reduce the water usage. This method (the Effect Modelling and Optimisation method) has been successfully applied to the chemical plants industry, the pulp and paper industry and the power plant. Instead of focusing on academic problems, I mainly developed my research based on industrial applications that lead to valuable and applicable patented results. Recently the methods developed have been extended to realise the thermoeconomic optimisation of integrated systems like fuel cells. My present R&D work concerns the application of multi-objective optimisation strategies in the design of processes and integrated energy conversion systems.
Since 2001, Im working in the Industrial Energy Systems Laboratory (LENI) of Ecole Polytechnique fédérale de Lausanne (EPFL) where Im leading the R&D activities in the field of Computer Aided Analysis and Design of Industrial Energy Systems with a major focus on sustainable energy conversion system development using thermo-economic optimisation methodologies. A part from the application and the development of process integration techniques, that remains my major field of expertise, the applications concern :
Rational use of water and energy in Industrial processes and industrial production sites : projects with NESTLE, EDF, VEOLIA and Borregaard (pulp and paper).Energy conversion and process design : biofuels from waste biomass (with GASNAT, EGO and PSI), water dessalination and waste water treatment plant (VEOLIA), power plant design (ALSTOM), Energy conversion from geothermal sources (BFE). Integrated energy systems in urban areas : together with SCANE and SIG (GE) and IEA annexe 42 for micro-cogeneration systems.
I as well contributed to the definition of the 2000 Watt society and to studies concerning the emergence of green technologies on the market in the frame of the Alliance for Global Sustainability.
