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Concept

Proteasome

Related lectures (26)

Protein Aggregation Mechanisms: C. elegans Model Insights

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Cell Cycle Regulation

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Protein Maturation: Post-Translational Modifications

Covers the maturation of proteins and the role of post-translational modifications in their functionality and regulation.

Molecular Glues: New Drug Modalities

Explores molecular glues as new drug modalities, focusing on binding forces, energetics, biomolecular interactions, quantification, drug development, and structural characterization.

Hsp70/JDP Proteostasis Network: Functional Proteomics

Explores the human Hsp70/JDP proteostasis network and its impact on cellular functions and ciliogenesis.

Enzyme Inhibition Mechanisms Log in to Mediaspace to watch this video

Covers enzyme inhibition mechanisms, drug modes of action, targeted protein degradation using PROTACs, and the bump-hole method for protein-ligand engineering.