Johan AuwerxJohan Auwerx is Professor at the École Polytechnique Fédérale in Lausanne, Switzerland, where he occupies the Nestle Chair in Energy Metabolism. Dr. Auwerx has been using molecular physiology and systems genetics to understand metabolism in health, aging and disease. Much of his work focused on understanding how diet, exercise and hormones control metabolism through changing the expression of genes by altering the activity of transcription factors and their associated cofactors. His work was instrumental for the development of agonists of nuclear receptors - a particular class of transcription factors - into drugs, which now are used to treat high blood lipid levels, fatty liver, and type 2 diabetes. Dr. Auwerx was amongst the first to recognize that transcriptional cofactors, which fine-tune the activity of transcription factors, act as energy sensors/effectors that influence metabolic homeostasis. His research validated these cofactors as novel targets to treat metabolic diseases, and spurred the clinical use of natural compounds, such as resveratrol, as modulators of these cofactor pathways.
Johan Auwerx was elected as a member of EMBO in 2003 and is the recipient of a dozen of international scientific prizes, including the Danone International Nutrition Award, the Oskar Minkowski Prize, and the Morgagni Gold Medal. His work is highly cited by his peers with a h-factor of over 100. He is an editorial board member of several journals, including Cell Metabolism, Molecular Systems Biology, The EMBO Journal, Journal of Cell Biology, Cell, and Science. Dr. Auwerx co-founded a handful of biotech companies, including Carex, PhytoDia, and most recently Mitobridge, and has served on several scientific advisory boards.
Dr. Auwerx received both his MD and PhD in Molecular Endocrinology at the Katholieke Universiteit in Leuven, Belgium. He was a post-doctoral research fellow in the Departments of Medicine and Genetics of the University of Washington in Seattle.
Patrick Daniel BarthProfessor Patrick Barth is Associate Professor at EPFL and Adjunct Associate Professor at Baylor College of Medicine, Houston, TX, USA. He received training in Physics, Chemistry and Biology (University of Paris, ENS) in France and performed his PhD at the Commissiariat a l'Energie Atomique in Saclay, France on structure/function studies of membrane proteins (photosystem I) using biochemical and biophysical experimental techniques. He carried out postdoctoral studies at University of California at Berkeley with Tom Alber on computational development for calculating protein electrostatics and designing de novo selective peptide inhibitors of cellular protein interactions. He then went to the University of Washington as a postdoctoral fellow and instructor in David Baker's laboratory to develop computational techniques in the software Rosetta for predicting and designing membrane protein structures. He started his independent career and received tenure at Baylor College of Medicine. He will continue at EPFL to marry computation and experiment for understanding the molecular determinants of signal transduction, as well as modeling and designing membrane proteins with novel functions for various synthetic biology and therapeutic applications.
Kevin SivulaSee webpage for more info limno.epfl.ch
Teaching & PhD PhD Students Odile Louise Andres, Arthur Eliot Bouchez, Benjamin Goldman, Nicolas Johannes Diercks, Aurélie Fanny Marie Célérien, Jiajun Li, Louise Marie Foltzer-De Cian, Melanie Victoria Johanning, Nils William Laurent Golay Past EPFL PhD Students Andrea Gasperini, Pauline Bornoz, Xavier Adrian Jeanbourquin, Xiaoyun Yu, Mathieu Steven Prévot, Muhammad Aiman Bin Rahmanudin Hamdan, Nhât-Tân Vuong, Yongpeng Liu, Arvindh Sekar, Barbara Alexandra Primera
Jean-François MolinariProfessor J.F. Molinari is the director of the Computational Solid Mechanics Laboratory (http://lsms.epfl.ch) at EPFL, Switzerland. He holds an appointment in the Civil Engineering institute, which he directed from 2013 to 2017, and a joint appointment in the Materials Science institute. He started his tenure at EPFL in 2007, and was promoted to Full Professor in 2012. He is currently an elected member of the Research Council of the Swiss National Science Foundation in Division 2 (Mathematics, Natural and Engineering Sciences), and co editor in chief of the journal Mechanics of Materials. J.F. Molinari graduated from Caltech, USA, in 2001, with a M.S. and Ph.D. in Aeronautics. He held professorships in several countries besides Switzerland, including the United States with a position in Mechanical Engineering at the Johns Hopkins University (2000-2006), and France at Ecole Normale Supérieure Cachan in Mechanics (2005-2007), as well as a Teaching Associate position at the Ecole Polytechnique de Paris (2006-2009). The work conducted by Prof. Molinari and his collaborators takes place at the frontier between traditional disciplines and covers several length scales from atomistic to macroscopic scales. Over the years, Professor Molinari and his group have been developing novel multiscale approaches for a seamless coupling across scales. The activities of the laboratory span the domains of damage mechanics of materials and structures, nano- and microstructural mechanical properties, and tribology. Li TangEducation and Training Postdoctoral Fellow, Massachusetts Institute of Technology, 2013 - 2016 Ph.D., University of Illinois at Urbana-Champaign, 2007 - 2012 B.S., Peking University, 2003-2007
Paolo BenettinI was born in Padova, Italy, in 1986. After high school, I started the Environmental Engineering program at the University of Padova (Bachelor and Master), where I followed the 'soil protection' curriculum. During my Master studies I spent a semester as Erasmus student at Wageningen University (Wageningen, the Netherlands) to follow courses in Hydrology. After graduation, I decided to bring my education further and I started a Ph.D. at the civil and environmental engineering department at the University of Padova. My Ph.D. thesis focused on hydrologic transport and travel time distributions at the catchment scale. My contribution to the subject included both new theoretical formulations and extensive numerical applications to real catchments. During my Ph.D., I also spent 7 months as visiting research fellow at Virginia Tech University (Blacksburg, USA). Since I arrived at EPFL as post-doc in 2015, I started being involved in field and experimental activities, which allowed me to learn about practical experimental problems. In 2017 I had the opportunity to by hired by the ECHO laboratory as a permanent scientist, conducting research in the field of catchment hydrology.
Thierry MeyerThierry Meyer received in 1986 a diploma degree (MSc) in chemical engineering from the Swiss Federal Institute of Technology at Lausanne (EPFL). He was awarded in 1989 a PhD at EPFL for his thesis on micromixing in highly viscous polymeric media. He joined the Institute of Chemical Engineering from 1989 till 1993 as senior scientist in the field of polymerization reactions. In 1994 he joined Ciba-Geigy SA in the pigment division as successively development chemist, head of development a.i. and finally production manager for high performance pigments. Returning to the Institute of Chemical Engineering at EPFL in Lausanne by the end of 1998, he was nominated maître denseignement et de recherche (MER) for leading a new research group in the field of polymers and supercritical fluids, and teaching to chemists, chemical engineers and material sciences, disciplines as process development, introduction to chemical engineering, polymer and organic chemistry at master and bachelor program. In 2005 he owned the responsibility of the Occupational Health and Safety of the school of basic sciences on top of his research activities dealing with risk management and supercritical fluids. He is presently teaching introduction to chemical engineering at bachelor level, risk management at master level and specific courses on safety and engineering risk management in continuing education. He acts also as consultant and expert in risk assessment and chemical engineering matters by the ICC (International Chamber of Commerce) of the World Business Organization, by several consultancy companies and by major and SMEs chemical industries. Thierry Meyer is currently member of several international associations of the European Federation of Chemical Engineering, American institution of chemical engineering, American chemical society and senior member of the American Institute of Chemical Engineers. He was elected chairman of the European Working Party on Polymer Reaction Engineering from 2001 till 2006. He his currently the Swiss academic member of the European Working Party on Loss Prevention and Safety Promotion as well as of the European Working Party on Education. He is member of several editorial boards: Chemical Engineering Research and Design, Macromolecular Reaction Engineering, Chemical Engineering and Technology, Journal of Chemical Health and Safety.
Florian Frédéric Vincent BreiderFlorian Breider obtained his PhD in the field of the stable isotope biogeochemistry from the University of Neuchatel in 2013. This was followed by seven months of postdoc at EPFL in the Atmospheric Particles Research Laboratory and two years as research associate at Tokyo Institute of Technology (Japan) where he conducted studies on nitrous oxide biogeochemistry in oceans. From 2015 to 2018, he was research scientist in the Laboratory for Water Quality and Treatment at EPFL where he conducted research on disinfection by-products and antibiotic resistant bacteria. Since May 2018, he is director of the Central Environmental Laboratory at the Institute of Environmental Engineering of EPFL.