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Concept

Heart valve

Related publications (29)

Heartbeat-evoked cortical responses: Underlying mechanisms, functional roles, and methodological considerations

Olaf Blanke, Hyeongdong Park

The heart continuously and cyclically communicates with the brain. Beyond homeostatic regulation and sensing, recent neuroscience research has started to shed light on brain-heart interactions in diverse cognitive and emotional processes. In particular, ne ...

2019

Numerical approximation of cardiac electro-fluid-mechanical models : coupling strategies for large-scale simulation

Antonello Gerbi

The mathematical modeling of the heart involves several challenges, which are intrinsically related to the complexity of its function. A satisfactory cardiac model must be able to describe a wide range of different processes, such as the evolution of the t ...

EPFL2018

Propagation-based phase-contrast synchrotron imaging of aortic dissection in mice: from individual elastic lamella to 3D analysis

Nikolaos Stergiopoulos, Bram Trachet, Lydia Aslanidou

In order to show the advantage and potential of propagation-based phase-contrast synchrotron imaging in vascular pathology research, we analyzed aortic medial ruptures in BAPN/AngII-infused mice, a mouse model for aortic dissection. Ascending and thoraco-a ...

Nature Research2018

Complex blood flow patterns in an idealized left ventricle: A numerical study

Alfio Quarteroni, Anna Tagliabue

In this paper, we study the blood flow dynamics in a three-dimensional (3D) idealized left ventricle of the human heart whose deformation is driven by muscle contraction and relaxation in coordination with the action of the mitral and aortic valves. We pro ...

American Institute of Physics2017

Fluid dynamics of an idealized left ventricle: the extended Nitsche's method for the treatment of heart valves as mixed time varying boundary conditions

Alfio Quarteroni, Anna Tagliabue

In this work, we study the blood flow dynamics in idealized left ventricles (LV) of the human heart modelled by the Navier-Stokes equations with mixed time varying boundary conditions. The latter are introduced for simulating the functioning of the aortic ...

Wiley2017

Integrated Heart-Coupling multiscale and multiphysics models for the simulation of the cardiac function

Alfio Quarteroni, Ricardo Esteban Ruiz Baier, Toni Mikael Lassila, Simone Rossi

Mathematical modeling of the human heart and its function can expand our understanding of various cardiac diseases, which remain the most common cause of death in the developed world. Like other physiological systems, the heart can be understood as a compl ...

Elsevier Science Sa2017

A patient-specific aortic valve model based on moving resistive immersed implicit surfaces

Alfio Quarteroni, Elena Faggiano

In this paper, we propose a full computational framework to simulate the hemodynamics in the aorta including the valve. Closed and open valve surfaces, as well as the lumen aorta, are reconstructed directly from medical images using new ad hoc algorithms, ...

Springer Heidelberg2017

Cardiovascular morphometry with high-resolution 3D magnetic resonance: First application to left ventricle diastolic dysfunction

Nikolaos Stergiopoulos, Orestis Vardoulis, Davide Piccini

In this study, an image-based morphometry toolset quantifying geometric descriptors of the left ventricle, aorta and their coupling is applied to investigate whether morphological information can differentiate between subjects affected by diastolic dysfunc ...

Elsevier2017

Experimental study of atrial fibrillation cycle length during rapid atrial septal pacing

Jean-Marc Vesin, Sasan Yazdani, Adrian Luca

Computer model-based simulations have shown that rapid stimulation at 60-100% of atrial fibrillation cycle length (AFCL) from a ring of electrodes located around the septum may induce local capture in both atria for most AF dynamics. The present study aims ...

2017