Stewart ColeProfessor Stewart Cole is an international authority in bacterial molecular-genetics and genomics. He has made outstanding contributions in several fields including: bacterial anaerobic electron transport; genome analysis of retroviruses and papillomaviruses; antibiotic resistance mechanisms; and the molecular microbiology of toxigenic clostridia. His studies on isoniazid and multidrug resistance in Mycobacterium tuberculosis, together with his pioneering work on the pathogenicity, evolution and genomics of the tubercle and leprosy bacilli, have made him an undisputed leader in the field of mycobacterial research. The findings of his research are of direct relevance to public health and disease-control in both the developing world and the industrialised nations. He has published over 250 scientific papers and review articles, and holds many patents.
Bruno LemaitrePersonal Webpage
http://brunolemaitre.ch
Personal Webpage http://brunolemaitre.ch
Teaching & PhD PhD Students Blandine Ribotta, Yao Tian, Désirée Popelka, Prince Kumar Sah, Siqi Wang, Kenan Krakovic, Nathan Alexandre Klotz Past EPFL PhD Students Sveta Chakrabarti, Olivier Binggeli, Jeremy Keith Herren, Juan Camilo Paredes Escobar, Alfred Chng, Maroun Bou Sleiman, Jan Paul Dudzic, Mario Gonzalo Garcia Arraez, Claudia Melcarne, Alice Marra, Bianca Marie Petrignani, Mark Austin Hanson, Alexia Laurie Carboni Andrea AblasserTeaching & PhD PhD Students Ekaterina Gorbacheva, Iris Arianna Dorschel, Tieliang Gan, Yu Meng Past EPFL PhD Students Simone Margret Haag, Sélène Glück, Marilena Wischnewski, Sophie Rivara, Natasha Samson Courses Immunology - advances and therapeutic implications BIO-479 The students acquire advanced level knowledge regarding the functioning of the (vertebrate) immune system. A strong focus is placed on the molecular mechanisms underlying innate and adaptive immune responses and their impl
Nikolaos StergiopoulosEducation
MTE, Managing the Technology Enterprise Program (2000), IMD, Lausanne
Ph.D. in Biomedical Engineering & Engineering Mechanics (1990) Iowa State University, Ames, Iowa.
MS in Biomedical Engineering (1987) Iowa State University, Ames, Iowa.
Diploma in Mechanical Engineering (1985) National Technical University of Athens.
Professional Activities
2002 - present: Professor and director of LHTC
2010 - present: Founder and director of Rheon Medical SA, Préverenges, Switzerland
2008 - present: Founder and director of Antlia S.A., PSE-C, EPFL campus, Switzerland
1998 - 2007: Founder and Scientific Director of EndoArt S.A., Lausanne, Switzerland
1996 - 2002: Assistant professor at the Biomedical Engineering Laboratory, Swiss Federal Institute of Technology, Lausanne, Switzerland.
1991 - 1996: Research Associate at Swiss Federal Institute of Technology - Lausanne
1990 - 1991: Lecturer, Iowa State University
Hubert GiraultEducation: 1979 - Engineering diploma from Grenoble Institute of Technology. FRANCE. 1982 - PhD- Department of Chemistry, University of Southampton. Thesis entitled : Interfacial studies using drop image processing techniques. Positions : 1982 - 1984 SERC Research Fellow. University of Southampton. 1984 - 1985 CNRS Research Fellow. University of Southampton. 1985 - 1992 Lecturer in Physical Chemistry, University of Edinburgh. 1992 - Professor of Physical Chemistry, Ecole Polytechnique Fédérale de Lausanne. 2011 - 2014 Dean of Bachelor and Master studies Hubert Girault is the author of 2 textbooks, the co-author of about 600 scientific publications with more than 20'000 citations and the co-inventor of more than 15 patents. During his academic career, he has supervised 70 PhD students. 30 alumni of his laboratory are now Professors. Honours: Faraday medal 2006, Royal Society of Chemistry, Fellow of the International Society of Electrochemistry 2007, Reilley Award 2015. Fellow of the Electrochemical Society (USA), Shikata International medal, Polarography Society of Japan. Associate editor of Chemical Science
César PulgarinProf. C. Pulgarin is Chemist from Lausanne University, Master in environmental chemistry from Geneva University, Ph D in synthesis bio-inspired of natural substances from Neuchâtel University. During his education he carried out several industrial trainings.
Since March 1989, he has been working at the EPFL where he is leader of the Advanced Oxidation Processes Group (GPAO) active in the development chemical, photochemical, electrochemical, ultrasonic processes, their coupling between them and with biological systems to degrade chemical and microbiological pollutants in water and air. He has an H index of 40 and he is the world most cited author in 1) TiO2 photo-assisted bacterial inactivation in water and 2) Coupling of photochemical and biological processes for pollutant degradation. He has been involved in ten African, South American and European international research projects. He has been Swiss representative in COST program 540.
Jean-Marie Drezet1992-1996: PhD work at Laboratoire de Métallurgie Physique under the supervision of Prof. Michel Rappaz (cf : http://library.epfl.ch/theses/?display=detail&nr=1509) 1997-2000: EMPACT project (European Modelling Programme for Aluminium Casting Technologies) 2001-2004: VIRCAST project (European Virtual Casting) 2005-2006: Study of the sawing process of rolling sheet al. ingots (Alcan Fonds) 2005-2006: WelAIR project (Welding of Airframes, EADS) 2005-2008: study of the electron beam welding of Cu-Cr-Zr alloys (CEA, France) 2006-2008: study of the laser beam welding of Al-Li alloys (EADS, France) 2008-2011: co-supervision with Prof. A. Nussbaumer of the PhD work of C. Acevedo on the influence of residual stresses on the fatigue design of tubular welded joints, http://library.epfl.ch/theses/?nr=5056 2007-2010: co-supervision with Prof. J.-F. Molinari of the PhD work of K. Shahim on the Normal Pressure Hydrocephalus (S. Momjian, HU-Genève et R. Sinkus, ESPCI-Paris), http://library.epfl.ch/theses/?nr=5191 2008-2012: co-supervision with Prof. M. Rappaz of the PhD work of M. Sistaninia on the simulation of solidification cracking using granular models (CCMX-MERU project) 2010-2014: supervision with Prof. M. Rappaz of the PhD work of N. Chobaut on the modelling of stresses during quenching of thick heat treatable aluminium parts (CCMX-MERU project) 2011-2015: supervision with Prof. H. Van Swygenhoven-Moens of the PhD work of P. Schloth on precipitation during quenching of thick heat treatable aluminium parts (CCMX-MERU project) Graham KnottGraham Knott received his degree in physiology from the University of Southampton, UK, in 1990, and his PhD in neuroscience from the University of Tasmania, Australia, in 1995. He moved to the University of Lausanne in Switzerland in 1999 where he researched the plasticity of neuronal connectivity in the adult brain, developing correlative light and electron microscopy methods for the analysis of in vivo imaged neurons. In 2006 Graham joined the Ecole Polytechnique Fédérale de Lausanne, establishing the Bio Electron Microscopy Facility and has continued his research interests in brain plasticity and 3D electron microscopy.
Vassily HatzimanikatisDr. Vassily Hatzimanikatis is currently Associate Professor of Chemical Engineering and Bioengineering at Ecole Polytechnique Federale de Lausanne (EPFL), in Lausanne, Switzerland. Vassily received a PhD and an MS in Chemical Engineering from the California Institute of Technology, and his Diploma in Chemical Engineering from the University of Patras, in Greece. After the completion of his doctoral studies, he held a research group leader position at the Swiss Federal Institute of Technology in Zurich (ETHZ), Switzerland. Prior to joining EPFL, Vassily worked for three years in DuPont, Cargill, and Cargill Dow, and he has been assistant professor at Northwestern University, at Illinois, USA.
Vassilys research interests are in the areas of computational systems biology, biotechnology, and complexity. He is associate editor of the journals Biotechnology & Bioengineering, Metabolic Engineering and Integrative Biology, and he serves on the editorial advisory board of the journals Bioprocess and Biosystems Engineering, Journal of Chemical Technology and Biotechnology, and Industrial Biotechnology. He has written over 70 technical publications and he is co-inventor in three patents and patent applications.
Vassily is a fellow of the American Institute for Medical and Biological Engineering (2010), he was a DuPont Young Professor (2001-2004), and he has also received the Jay Bailey Young Investigator Award in Metabolic Engineering (2000), and the ACS Elmar Gaden Award (2011).
Johan AuwerxJohan Auwerx is Professor at the École Polytechnique Fédérale in Lausanne, Switzerland, where he occupies the Nestle Chair in Energy Metabolism. Dr. Auwerx has been using molecular physiology and systems genetics to understand metabolism in health, aging and disease. Much of his work focused on understanding how diet, exercise and hormones control metabolism through changing the expression of genes by altering the activity of transcription factors and their associated cofactors. His work was instrumental for the development of agonists of nuclear receptors - a particular class of transcription factors - into drugs, which now are used to treat high blood lipid levels, fatty liver, and type 2 diabetes. Dr. Auwerx was amongst the first to recognize that transcriptional cofactors, which fine-tune the activity of transcription factors, act as energy sensors/effectors that influence metabolic homeostasis. His research validated these cofactors as novel targets to treat metabolic diseases, and spurred the clinical use of natural compounds, such as resveratrol, as modulators of these cofactor pathways.
Johan Auwerx was elected as a member of EMBO in 2003 and is the recipient of a dozen of international scientific prizes, including the Danone International Nutrition Award, the Oskar Minkowski Prize, and the Morgagni Gold Medal. His work is highly cited by his peers with a h-factor of over 100. He is an editorial board member of several journals, including Cell Metabolism, Molecular Systems Biology, The EMBO Journal, Journal of Cell Biology, Cell, and Science. Dr. Auwerx co-founded a handful of biotech companies, including Carex, PhytoDia, and most recently Mitobridge, and has served on several scientific advisory boards.
Dr. Auwerx received both his MD and PhD in Molecular Endocrinology at the Katholieke Universiteit in Leuven, Belgium. He was a post-doctoral research fellow in the Departments of Medicine and Genetics of the University of Washington in Seattle.
Horst PickTeaching & PhD PhD Students Vivek Prakash, Yang Wang Past EPFL PhD Students as codirector Olivia Baud, Thamani Dahoun, Enio Daniel Zanchetta Courses Biotechnology lab (for CGC) ChE-433 This laboratory-training course is designed to give students a comprehensive insight into laboratory research techniques in the field of biotechnology and pharmaceutical biotechnology with practices employed in the industry. Accompanying lectures provide the theoretical background. Chemosensory receptors:
Claudio BruschiniClaudio Bruschini holds an MSc in high energy physics from the University of Genova and a PhD in Applied Sciences from the Vrije Universiteit Brussel (VUB). He started his career with INFN (Italy, 1993), in the WA92 CERN collaboration (particle physics), and then moved to CERN as a Fellow in the European GP-MIMD2 project, attached to the NA48 collaboration (particle physics, parallel programming, 1994-1995). He then started his close collaboration with EPFL, first in the DeTeC (Demining Technology Center) project (sensors for landmine detection/humanitarian demining, 1996-1997). After DeTeC's end, he started the first of a series of fruitful collaborations with the Vrije Universiteit Brussel (VUB) on humanitarian demining related R&D (1998). This was followed by the EUDEM survey project (The European Union in Humanitarian Demining, 1998), the EUDEM2 three year EC sponsored support measure (www.eudem.info, 2001-2004), and the DELVE support action (www.delve.vub.ac.be, 2007). In parallel he started working within the EPFL's AQUA group (Advanced Quantum Architectures, Edoardo Charbon), on topics as diverse as ultrasonic sensors for in-air application, optical 3D and high speed 2D sensing, sensor networks, or tracking/motion capture systems, in particular for the preparation of research projects. This culminated in the European MEGAFRAME (www.megaframe.eu, FP6, 2006-2010, SPAD arrays and related in-pixel time stamping electronics in deep submicron CMOS technology) and SPADnet (www.spadnet.eu, FP7, 2010-2014, networked SPAD arrays for Positron Emission Tomography) projects, coordinated by EPFL-AQUA. As from 2009 he also worked with Dario Floreano on the management of the CURVACE Curved Artificial Compound Eyes FP7 project (www.curvace.org), coordinated by EPFL-LIS. He was also active with CHUV (Lausanne University Hospital) within EndoTOFPET-US (endoscopic PET) as well as on a CTI project devoted to the development of a new hand-held standalone tool for tracer-guided medical procedures. In 2014 he had also the pleasure of joining the EPFL ICLAB of Christian Enz during its ramp-up phase, collaborating on device related topics (SNF GigaRadMOST) and biomedical R&D (NanoTera WiseSkin). Claudio is now fully with EPFL’s Advanced Quantum Architecture (AQUA). He has also been active as independent scientific consultant, under the label CBR Scientific Consulting, on the preparation of (European) R&D project proposals and the execution of individual studies, and worked in 2006 for a local start-up as operations manager and R&D advisor.... but this is another story. An unauthorized early biography is available at http://lami.epfl.ch/team/claudiob/... Edoardo CharbonEdoardo Charbon (SM’00 F’17) received the Elektrotechnik Diploma from ETH Zurich, the M.S. from the University of California at San Diego, and the Ph.D. from the University of California at Berkeley in 1988, 1991, and 1995, respectively, all in electrical engineering and EECS. He has consulted with numerous organizations, including Bosch, X-Fab, Texas Instruments, Maxim, Sony, Agilent, and the Carlyle Group. He was with Cadence Design Systems from 1995 to 2000, where he was the architect of the company's initiative on information hiding for intellectual property protection. In 2000, he joined Canesta Inc., as the Chief Architect, where he led the development of wireless 3-D CMOS image sensors. Since 2002 he has been a member of the faculty of EPFL, where is a full professor since 2015. From 2008 to 2016 he was full professor and chair at the Delft University of Technology, where he spearheaded the university's effort on cryogenic electronics for quantum computing as part of QuTech. He has been the driving force behind the creation of deep-submicron CMOS SPAD technology, which is mass-produced since 2015 and is present in smartphones, telemeters, proximity sensors, and medical diagnostics tools. His interests span from 3-D vision, LiDAR, FLIM, FCS, NIROT to super-resolution microscopy, time-resolved Raman spectroscopy, and cryo-CMOS circuits and systems for quantum computing. He has authored or co-authored over 400 papers and two books, and he holds 23 patents. Dr. Charbon is a distinguished visiting scholar of the W. M. Keck Institute for Space at Caltech, a fellow of the Kavli Institute of Nanoscience Delft, a distinguished lecturer of the IEEE Photonics Society, and a fellow of the IEEE.
Harm-Anton KlokExpertise
Polymer design at nanoscaleBiologically-inspired polymers
Mission
Research at the Laboratory of Polymer (LP) focuses on the development of novel advanced polymeric materials with potential applications in optics, electronics or medicine. The philosophy is that precise control over nanoscale structure is an important prerequisite to tailor polymer properties. To this end, a “bottom-up” approach is followed, which starts with designing a new material at the molecular level, in order to be able to pr
