Lectures related to Active site

Event Mobility Planning MOOC: Mobility planning

Explores leisure mobilities related to events, modal shares, and traffic management proposals.

Introduces implantable bio-fuel cells, focusing on their working principle, design, milestones, and applications in biomedical devices.

Catalytic Mechanisms: Selectivity and Efficiency

Covers catalytic mechanisms at 180°C, focusing on selectivity and efficiency.

Enzymatic Catalysis & Inhibition

Explores enzymatic catalysis mechanisms and inhibition dynamics in catalysis and polymerization.

Protein Function Regulation: Degradation Mechanisms

Covers the mechanisms of protein degradation, including the roles of the proteasome and autophagy in regulating protein function.

Protein Structure Determination

Explores protein structure determination using NMR and Cryo-EM techniques, covering chemical shifts, isotope labeling, NOE, and high-resolution imaging methods.

Enzymes: Catalytic Strategies

Explores enzyme catalytic strategies, including proteases and carbonic anhydrase, inhibition mechanisms, and specificity of serine proteases.

Biopolymers and Biomembranes

Explores the importance of biopolymers and biomembranes in cell mechanics and their flexibility under thermal fluctuations.

Kinetics: Reaction Rates and Equilibrium

Explores reaction kinetics, rate laws, measurement techniques, and binding kinetics between ligands and proteins.

Activity-based Protein Profiling: Druggable Sites Identification

Explores Activity-based Protein Profiling for druggable site identification and strategies to minimize off-target reactivity of covalent inhibitors.

Cellular Communication and Metabolism: Energy Transformation Principles

Discusses cellular communication, metabolism, energy transformation, and the role of enzymes in biochemical reactions.

Publication Analysis: Understanding Research Articles

Introduces publication analysis, emphasizing critical evaluation of research articles and effective reading strategies.

Introduction into Catalysis: Basics and Mechanisms

Introduces the basics of catalysis, including types of catalysis, energy profiles, and the importance of catalysts in speeding up reactions.

Hsp70 Chaperone Binding: Substrate Selectivity and Function

Explores the selective promiscuity in binding of the E. coli Hsp70 chaperone to unfolded or misfolded protein substrates, examining its implications in protein folding mechanisms.

Enzymes: Catalytic Strategies

Explores enzymes' catalytic strategies, including proteases and carbonic anhydrase, specificity, and pH influence on catalysis.

Enzyme Kinetics: Understanding Reaction Rates and Mechanisms

Covers enzyme kinetics, focusing on reaction rates, the Michaelis-Menten equation, and factors affecting enzyme activity.

Inclusion of Fermented Foods in Food Guides

Discusses the inclusion of fermented foods in global food guides, exploring their benefits and risks, enzyme kinetics, and the history of food enzymes.

Posttranslational Modifications: Phosphorylation and Protein Phosphatases

Covers posttranslational modifications, focusing on phosphorylation and protein phosphatases, and explains kinase specificity assays and the optimal phosphorylation consensus.

Protein Regulation: Hsp90 Chaperone Machinery

Explores molecular mechanisms of protein regulation in the Hsp90 chaperone machinery through experiments and analyses.

Introduction to Metabolism

Introduces the fundamental concepts of metabolism, including metabolic pathways, bioenergetics, ATP role, and enzyme catalysis.

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