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Concept

Local anesthetic

Related publications (15)

Ray-tracing MRT and human thermophysiology model combination for local discomfort prediction

Dolaana Khovalyg, Arnab Chatterjee, Mohamad Rida

Thermal comfort and discomfort based on the local sensation of different body parts have been an important development in thermal comfort studies from the past decade. The human thermophysiology model can be a handy tool to predict local skin and core temp ...

TU Delft2022

Repurposed drug combination via high-throughput screening and dual drug delivery system development for the treatment of retinoblastoma

Po-Jen Tseng

The goal of retinoblastoma (RB) treatment is to save the child's life, eyes and functional vision, with that order of priority. The management of RB is complex and involves strategically chosen methods of surgical enucleation, external beam radiotherapy, i ...

EPFL2022

Measuring Glycolytic Activity with Hyperpolarized [2H7, U-13C6] D-Glucose in the Naive Mouse Brain under Different Anesthetic Conditions

Rolf Gruetter, Bernard Lanz, Mor-Miri Mishkovsky, Andrea Capozzi, Yves Pilloud, Emmanuelle Ines Flatt

Glucose is the primary fuel for the brain; its metabolism is linked with cerebral function. Different magnetic resonance spectroscopy (MRS) techniques are available to assess glucose metabolism, providing complementary information. Our first aim was to inv ...

2021

Raspberry-Pi based system for propofol monitoring

Sandro Carrara, Danilo Demarchi, Francesca Stradolini, Tugba Kilic, Abuduwaili Tuoheti

Induction of anesthesia with propofol is a largely adopted technique in hospital environments. The correct dosage of this compound is essential to avoid under- or over-anesthesia that may result in serious side-effects. Therefore, in clinical settings, lon ...

ELSEVIER SCIENCE BV2018

Hybrid peripheral-spinal neuroprosthesis for refined motor execution after paralysis

Sophie Marie Marthe Wurth

Spinal cord injury (SCI) disrupts the communication between the brain and the spinal circuits responsible for movement, thereby causing severe motor deficits. Current strategies to restore function to paralyzed limbs have separately investigated electrical ...

EPFL2018

Xenon Recovery at Room Temperature using Metal-Organic Frameworks

Daniele Ongari

Xenon is known to be a very efficient anesthetic gas, but its cost prohibits the wider use in medical industry and other potential applications. It has been shown that Xe recovery and recycling from anesthetic gas mixtures can significantly reduce its cost ...

Wiley-Blackwell2017

Cascaded PID controller for anaesthesia delivery

Alena Simalatsar

The technologies for continuous measurement of the anaesthetic agents circulating in body fluids are not mature yet, though some preliminary prototypes exist already. We present a control algorithm that based on the real measurement of propofol plasma conc ...

2016

Molecular beam epitaxy of InAs nanowires in SiO2 nanotube templates: challenges and prospects for integration of III-Vs on Si

Anna Fontcuberta i Morral, Heidi Andrea Potts, Jean-Baptiste Leran, Federico Matteini, Jelena Vukajlovic Plestina, Frank Meyer, Ruben Ricca

Guided growth of semiconductor nanowires in nanotube templates has been considered as a potential platform for reproducible integration of III-Vs on silicon or other mismatched substrates. Herein, we report on the challenges and prospects of molecular beam ...

Institute of Physics2016

Microstructure informed tractography: pitfalls and open challenges

Jean-Philippe Thiran, Alessandro Daducci, Maxime Descoteaux

One of the major limitations of diffusion MRI tractography is that the fiber tracts recovered by existing algorithms are not truly quantitative. Local techniques for estimating more quantitative features of the tissue microstructure exist, but their combin ...

Frontiers Research Foundation2016

Cholinergic Signals in Mouse Barrel Cortex during Active Whisker Sensing

Carl Petersen, Sylvain Crochet, Yves Emile Alfred Kremer

Internal brain states affect sensory perception, cognition, and learning. Many neocortical areas exhibit changes in the pattern and synchrony of neuronal activity during quiet versus active behaviors. Active behaviors are typically associated with desynchr ...

Elsevier2014

Patch-based methods for variational image processing problems

Emmanuel D'Angelo

Image Processing problems are notoriously difficult. To name a few of these difficulties, they are usually ill-posed, involve a huge number of unknowns (from one to several per pixel!), and images cannot be considered as the linear superposition of a few p ...

EPFL2013

Automatic Mallampati Classification Using Active Appearance Models

Jean-Philippe Thiran, Matteo Sorci, Anil Yuce, Gabriel Louis Cuendet

Difficult tracheal intubation assessment is an important research topic in anesthesia as failed intubations are important causes of mortality in anesthetic practice. The modified Mallampati score is widely used, alone or in conjunction with other criteria, ...

2012

Modeling the Gabaergic Action of Etomidate on the Thalamocortical System

Sean Lewis Hill

BACKGROUND: We have used a computational model of the thalamocortical system to investigate the effects of a GABAergic anesthetic (etomidate) on cerebral cortical and thalamic neuronal function. We examined the effects of phasic an tonic inhibition, as wel ...

2009

Modeling the effects of midazolam on cortical and thalamic neurons

Sean Lewis Hill

Controversy exists regarding the site where anesthetics act in the brain to produce sedation and unconsciousness. Actions in the cerebral cortex and thalamus are likely, although the relative importance of each site is unclear. We used in computo modeling ...

2009

Local properties of the Hochschild cohomology of C*-algebras

Let A be a C*-algebra, and let X be a Banach A-bimodule. Johnson [B. E. Johnson, 'Local derivations on C*-algebras are derivations', Trans. Amer Math. Soc. 353 (2000), 313-325] showed that local derivations from A into X are derivations. We extend this con ...

Cambridge University Press2008