Stéphane JoostExpertise
Geographic Information Science and spatial statisticsMolecular ecology, Landscape genomics, Seascape genomicsSpatial epidemiology, Health geographics
Publications Publications- List of publications
Teaching & PhD PhD Students Marco André Vieira Ruas, Manon Laetitia Pribille, Martine Valérie Besse Past EPFL PhD Students Estelle Rochat, Solange Catherine Gaillard, Oliver Michele Selmoni, Anaïs Ladoy, Annie Sandrine Guillaume Past EPFL PhD Students as codirector Sylvie Stucki, Kevin Leempoel, Martí
Mathew Magimai DossTeaching & PhD PhD Students Karl El Hajal, Tilak Purohit Past EPFL PhD Students as codirector Ramya Rasipuram, Marzieh Razavi, Hannah Muckenhirn, Sandrine Tornay, Subrahmanya Pavankumar Dubagunta, Enno Hermann, Julian David Fritsch, Neha Tarigopula, Mostaani Zohreh, Eklavya Sarkar Courses Automatic speech processing EE-554 The goal of this course is to provide the students with the main formalisms, models and algorithms required for the implementation of advanced speech processing applicat
Sébastien MarcelExpertise
image processing, pattern recognition, machine learning, biometrics
Current work
Face recognitionSpeaker recognitionMobile biometrics ( http://www.mobioproject.org )Spoofing ( http://www.tabularasa-euproject.org )Biometrics evaluation and testing ( http://www.beat-eu.org )
Sébastien Marcel is the head of the Biometrics group and senior research scientist at the Idiap Research Institute (CH), where he leads a research team and conducts research on biometrics and more particularly face recognition, Klaus Benedikt SchönenbergerVision: Scientific research and technology development can be mobilized to help the poorest and most vulnerable in this world. Klaus Schönenberger obtained an MSc in Microengineering (1993), followed by a PhD (1996) from the Swiss Federal Institute of Technology in Lausanne (EPFL). After a post-doc at Lawrence Livermore National Laboratory in California, he spent over 10 years in the medical devices industry in leading positions such as Vice-President of Worldwide R&D in a 100mcompanyandGlobalVice−ResidentofResearchandTechnologyina1bn company. In 2009, as he was working for a medical devices company, he received a shock: he realized that there is a huge imbalance in access to medical technology in industrialized versus low and middle-income countries. After a closer look, he discovered that he imbalance’s main cause is a mismatch between existing technologies and business models, with those needed in low and middle-income countries. He decided to leave industry and, in 2009, he co-founded the EssentialMed Foundation, an innovative non-profit venture. In 2011, realizing that both technology and business models needed a profound rethinking, he joined EPFL where he launched EssentialTech, an initiative inspired by the philosophy of EssentialMed but expanded to a much wider portfolio of "essential" technologies. The university-wide program aims to develop innovative technologies and business models, for the benefit of sustainable development in low and middle-income countries. In this role, he has already launched and overseen a dozen large projects. Major Humanitarian actors such as the ICRC, MSF and Terre des Hommes took notice of the innovative approach proposed, and decided to collaborate in 2015-2016. This has resulted notably in the joint creation between EPFL and ICRC, of the Humanitarian Tech Hub at EPFL. In May 2017, Klaus directed and launched a MOOC(Massive Open Online Course) entitled “Technology Innovation for Sustainable Development” which aims to spread the unique methodology and approach worldwide. As of today, more than 6000 people have enrolled. In 2018 a first spin-off company was created. Award winning Pristem SA will deploy an innovative new digital xray imaging system, specifically designed for low-income contexts. In December 2018, the creation of the EssentialTech centre was announced by EPFL's presidency, and Klaus is now the Centre's director. Another spin-off of the EssentialTech Centre is the company HMCare, launched in 2020, which is deploying a transparent surgical mask. Antoine BosselutAntoine Bosselut is an assistant professor at EPFL. He leads the EPFL NLP group, which conducts research on natural language processing (NLP) systems that can model, represent, and reason about human and world knowledge.
Prior to joining EPFL, he was a postdoctoral researcher at Stanford University working in the
SNAP
and
NLP
groups and a young investigator on the
Mosaic
project at the
Allen Institute for AI
. He completed his PhD at the University of Washington.
Denis GilletDenis Gillet received the Diploma in Electrical Engineering from the Swiss Federal Institute of Technology in Lausanne (EPFL) in 1988, and the Ph.D. degree in Information Systems also from the EPFL in 1995. During 1992 he was appointed as Research Fellow at the Information Systems Laboratory of Stanford University in the United States. He is currently Maître d'enseignement et de recherche at the EPFL School of Engineering, where he leads the React research group. His current research interests include Technologies Enhanced Learning (TEL), Human Computer Interaction (HCI), Human Devices Interaction (HDI) and Optimal Coordination of Complex and Distributed Systems. Denis Gillet is affiliated at EPFL with the Center for Intelligent Systems and the Center for Digital Education.
Jürgen BruggerI am a Professor of Microengineering and co-affiliated to Materials Science. Before joining EPFL I was at the MESA Research Institute of Nanotechnology at the University of Twente in the Netherlands, at the IBM Zurich Research Laboratory, and at the Hitachi Central Research Laboratory, in Tokyo, Japan. I received a Master in Physical-Electronics and a PhD degree from Neuchâtel University, Switzerland. Research in my laboratory focuses on various aspects of MEMS and Nanotechnology. My group contributes to the field at the fundamental level as well as in technological development, as demonstrated by the start-ups that spun off from the lab. In our research, key competences are in micro/nanofabrication, additive micro-manufacturing, new materials for MEMS, increasingly for wearable and biomedical applications. Together with my students and colleagues we published over 200 peer-refereed papers and I had the pleasure to supervise over 25 PhD students. Former students and postdocs have been successful in receiving awards and starting their own scientific careers. I am honoured for the appointment in 2016 as Fellow of the IEEE “For contributions to micro and nano manufacturing technology”. In 2017 my lab was awarded an ERC AdvG in the field of advanced micro-manufacturing.
Henry MarkramHenry Markram started a dual scientific and medical career at the University of Cape Town, in South Africa. His scientific work in the 80s revealed the polymodal receptive fields of pontomedullary reticular formation neurons in vivo and how acetylcholine re-organized these sensory maps.
He moved to Israel in 1988 and obtained his PhD at the Weizmann Institute where he discovered a link between acetylcholine and memory mechanisms by being the first to show that acetylcholine modulates the NMDA receptor in vitro studies, and thereby gates which synapses can undergo synaptic plasticity. He was also the first to characterize the electrical and anatomical properties of the cholinergic neurons in the medial septum diagonal band.
He carried out a first postdoctoral study as a Fulbright Scholar at the NIH, on the biophysics of ion channels on synaptic vesicles using sub-fractionation methods to isolate synaptic vesicles and patch-clamp recordings to characterize the ion channels. He carried out a second postdoctoral study at the Max Planck Institute, as a Minerva Fellow, where he discovered that individual action potentials propagating back into dendrites also cause pulsed influx of Ca2 into the dendrites and found that sub-threshold activity could also activated a low threshold Ca2 channel. He developed a model to show how different types of electrical activities can divert Ca2 to activate different intracellular targets depending on the speed of Ca2 influx an insight that helps explain how Ca2 acts as a universal second messenger. His most well known discovery is that of the millisecond watershed to judge the relevance of communication between neurons marked by the back-propagating action potential. This phenomenon is now called Spike Timing Dependent Plasticity (STDP), which many laboratories around the world have subsequently found in multiple brain regions and many theoreticians have incorporated as a learning rule. At the Max-Planck he also started exploring the micro-anatomical and physiological principles of the different neurons of the neocortex and of the mono-synaptic connections that they form - the first step towards a systematic reverse engineering of the neocortical microcircuitry to derive the blue prints of the cortical column in a manner that would allow computer model reconstruction.
He received a tenure track position at the Weizmann Institute where he continued the reverse engineering studies and also discovered a number of core principles of the structural and functional organization such as differential signaling onto different neurons, models of dynamic synapses with Misha Tsodyks, the computational functions of dynamic synapses, and how GABAergic neurons map onto interneurons and pyramidal neurons. A major contribution during this period was his discovery of Redistribution of Synaptic Efficacy (RSE), where he showed that co-activation of neurons does not only alter synaptic strength, but also the dynamics of transmission. At the Weizmann, he also found the tabula rasa principle which governs the random structural connectivity between pyramidal neurons and a non-random functional connectivity due to target selection. Markram also developed a novel computation framework with Wolfgang Maass to account for the impact of multiple time constants in neurons and synapses on information processing called liquid computing or high entropy computing.
In 2002, he was appointed Full professor at the EPFL where he founded and directed the Brain Mind Institute. During this time Markram continued his reverse engineering approaches and developed a series of new technologies to allow large-scale multi-neuron patch-clamp studies. Markrams lab discovered a novel microcircuit plasticity phenomenon where connections are formed and eliminated in a Darwinian manner as apposed to where synapses are strengthening or weakened as found for LTP. This was the first demonstration that neural circuits are constantly being re-wired and excitation can boost the rate of re-wiring.
At the EPFL he also completed the much of the reverse engineering studies on the neocortical microcircuitry, revealing deeper insight into the circuit design and built databases of the blue-print of the cortical column. In 2005 he used these databases to launched the Blue Brain Project. The BBP used IBMs most advanced supercomputers to reconstruct a detailed computer model of the neocortical column composed of 10000 neurons, more than 340 different types of neurons distributed according to a layer-based recipe of composition and interconnected with 30 million synapses (6 different types) according to synaptic mapping recipes. The Blue Brain team built dozens of applications that now allow automated reconstruction, simulation, visualization, analysis and calibration of detailed microcircuits. This Proof of Concept completed, Markrams lab has now set the agenda towards whole brain and molecular modeling.
With an in depth understanding of the neocortical microcircuit, Markram set a path to determine how the neocortex changes in Autism. He found hyper-reactivity due to hyper-connectivity in the circuitry and hyper-plasticity due to hyper-NMDA expression. Similar findings in the Amygdala together with behavioral evidence that the animal model of autism expressed hyper-fear led to the novel theory of Autism called the Intense World Syndrome proposed by Henry and Kamila Markram. The Intense World Syndrome claims that the brain of an Autist is hyper-sensitive and hyper-plastic which renders the world painfully intense and the brain overly autonomous. The theory is acquiring rapid recognition and many new studies have extended the findings to other brain regions and to other models of autism.
Markram aims to eventually build detailed computer models of brains of mammals to pioneer simulation-based research in the neuroscience which could serve to aggregate, integrate, unify and validate our knowledge of the brain and to use such a facility as a new tool to explore the emergence of intelligence and higher cognitive functions in the brain, and explore hypotheses of diseases as well as treatments.