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Concept

Elderly care

Related publications (22)

Impact of the Natural Compound Urolithin A on Health, Disease, and Aging

Johan Auwerx, Davide D'Amico, Pamela Solange Valdés Undurraga, Pénélope Andreux

Urolithin A (UA) is a natural compound produced by gut bacteria from ingested ellagitannins (ETs) and ellagic acid (EA), complex polyphenols abundant in foods such as pomegranate, berries, and nuts. UA was discovered 40 years ago, but only recently has its ...

2021

Gamified Motor Training With Tangible Robots in Older Adults: A Feasibility Study and Comparison With the Young

Pierre Dillenbourg, Friedhelm Christoph Hummel, Wafa Monia Benkaouar Johal, Maximilian Jonas Wessel, Arzu Güneysu Özgür, Ayberk Özgür, Jennifer Kaitlyn Olsen

Background: An increasing lifespan and the resulting change in our expectations of later life stages are dependent on a good health state. This emphasizes the importance of the development of strategies to further strengthen healthy aging. One important as ...

2020

Evaluation of 1-Year in-Home Monitoring Technology by Home-Dwelling Older Adults, Family Caregivers, and Nurses

Daniel Gatica-Perez, Philipp Buluschek

Introduction:Population aging is increasing the needs and costs of healthcare. Both frailty and the chronic diseases affecting older people reduce their ability to live independently. However, most older people prefer to age in their own homes. New develop ...

2020

Transsphenoidal resection for pituitary adenoma in elderly versus younger patients: a systematic review and meta-analysis

Constantin Tuleasca

Introduction Pituitary adenomas (PA) are common intracranial tumors. In the context of the aging of the population, the question is whether postsurgical outcomes are comparable to the younger ones. The primary objective of the present study was to review p ...

2020

Recommender System for Responsive Engagement of Senior Adults in Daily Activities

Pearl Pu Faltings, Igor Kulev

Understanding and predicting how people change their behavior after an intervention from time series data is an important task for health recommender systems. This task is especially challenging when the time series data is frequently sampled. In this pape ...

SPRINGER INTERNATIONAL PUBLISHING AG2020

New Measurement Method in Drug Sensing by Direct Total-Charge Detection in Voltammetry

Sandro Carrara, Danilo Demarchi, Simone Aiassa

Electrochemical biosensors are promoting point-of-care and wearable instrumentation due to their high versatility in measuring human metabolites. There is a considerable number of biological compounds that can be detected and measured through voltammetry b ...

IEEE2020

Age-Dependent Asymmetry of Wrist Position Sense Is Not Influenced by Stochastic Tactile Stimulation

Jamie Paik, Harshal Arun Sonar

Stochastic stimulation has been shown to improve movement, balance, the sense of touch, and may also improve position sense. This stimulation can be non-invasive and may be a simple technology to enhance proprioception. In this study, we investigated wheth ...

2020

A biosensor for measuring NAD(+) levels at the point of care

Johan Auwerx, Kai Johnsson, Luc Patiny, Elena Katsyuba, Lin Xue, Qiuliyang Yu

The cellular level of nicotinamide adenine dinucleotide (NAD(+)), through its different functions, affects cellular metabolism and signalling(1-3). A decrease in the NAD(+) content has been associated with various pathologies and physiological aging(4,5), ...

NATURE PUBLISHING GROUP2019

The mitophagy activator urolithin A is safe and induces a molecular signature of improved mitochondrial and cellular health in humans

Johan Auwerx, Patrick Aebischer, Dongryeol Ryu, Pénélope Andreux

Urolithin A (UA) is a natural dietary, microflora-derived metabolite shown to stimulate mitophagy and improve muscle health in old animals and in preclinical models of aging(1). Here, we report the results of a first-in-human clinical trial in which we adm ...

NATURE PUBLISHING GROUP2019

Electrically Assisted Movement Therapy in Chronic Stroke Patients With Severe Upper Limb Paresis: A Pilot, Single-Blind, Randomized Crossover Study

José del Rocio Millán Ruiz, Silvio Ionta, Stephanie Clarke, Andrea Biasiucci, Andrea Maesani

Objective To evaluate the effects of electrically assisted movement therapy (EAMT) in which patients use functional electrical stimulation, modulated by a custom device controlled through the patient's unaffected hand, to produce or assist task-specific up ...

Elsevier2017

Stability against backward balance loss: Age-related modifications following slip-like perturbations of multiple amplitudes

Silvestro Micera

Falls are one of the most serious problems in the elderly. Although previous studies clearly link the increased risk of falls with ageing, the mechanisms responsible for the modifications of reactive motor behaviours in response to external perturbations a ...

Elsevier Ireland Ltd2017

Anomaly detection in elderly daily behavior in ambient sensing environments

Daniel Gatica-Perez

Current ubiquitous computing applications for smart homes aim to enhance people’s daily living respecting age span. Among the target groups of people, elderly are a population eager for “choices for living arrangements”, which would allow them to continue ...

Springer Int Publishing Ag2016

Instrumented shoes for activity classification in the elderly

Kamiar Aminian, Anisoara Ionescu, Christopher Moufawad El Achkar

Quantifying daily physical activity in older adults can provide relevant monitoring and diagnostic information about risk of fall and frailty. In this study, we introduce instrumented shoes capable of recording movement and foot loading data unobtrusively ...

Elsevier2016

A Ball-Screw Driven Motorized Hip Orthosis

Hannes Bleuler, Mohamed Bouri, Reymond Clavel, Amalric Louis Ortlieb, Jeremy Olivier

In this paper we present a motorized hip orthosis to assist elderly people while walking, stair climbing and during the sit-to-stand transitions. The design is based on biomechanics considerations. Ranges of motion, velocities and torques of the hip joint ...

2014

The effects on biomechanics of walking and balance recovery in a novel pelvis exoskeleton during zero-torque control

Silvestro Micera

Fall-related accidents are among the most serious concerns in elderly people, amputees and subjects with neurological disorders. The aim of this paper was to investigate the behaviour of healthy subjects wearing a novel light-weight pelvis exoskeleton cont ...

Cambridge University Press2014

Serum profiling of healthy aging identifies phospho- and sphingolipid species as markers of human longevity

As centenarians well represent the model of healthy aging, there are many important implications in revealing the underlying molecular mechanisms behind such successful aging. By combining NMR metabonomics and shot-gun lipidomics in serum we analyzed metab ...

Impact Journals Llc2014

Gait disturbances as specific predictive markers of the first fall onset in elderly people: a two-year prospective observational study

Jean-Baptiste Mignardot

Falls are common in the elderly, and potentially result in injury and disability. Thus, preventing falls as soon as possible in older adults is a public health priority, yet there is no specific marker that is predictive of the first fall onset. We hypothe ...

Frontiers Research Foundation2014

Development of an Assistive Motorized Hip Orthosis

Hannes Bleuler, Mohamed Bouri, Reymond Clavel, Jeremy Olivier, Amalric Louis Ortlieb

With the increase of life expectancy, a higher number of elderly need assistance to maintain their mobility and their independance. The hip joint is crucial for walking and is problematic for a large number of aged people. In this paper we present a novel ...

2013

Assessment of Body Motion and Muscle Weakness : Outcome Evaluation in Frail Elderly and DMD Subjects

Raluca Lidia Ganea

Muscle weakness is a common symptom in elderly population and in children with Duchenne muscular dystrophy (DMD), causing impaired mobility. DMD is a devastating degenerative disease caused by a mutation in the dystrophin gene, leading to the absence of th ...

EPFL2011

Multi-parametric Evaluation of Sit-to-Stand and Stand-to-Sit Transitions in Elderly People

Kamiar Aminian, Anisoara Ionescu, Raluca Lidia Ganea

The aim of this study was to extract multi-parametric measures characterizing different features of sit-to-stand (Si-St) and stand-to-sit (St-Si) transitions in older persons, using a single inertial sensor attached to the chest. Investigated parameters we ...

2011