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Concept

Relative biological effectiveness

Related publications (10)

Establishment of a Therapeutic Ratio for Gamma Knife Radiosurgery of Trigeminal Neuralgia: The Critical Importance of Biologically Effective Dose Versus Physical Dose

Constantin Tuleasca, Adrien Jean Régis Maurice Hilaire

OBJECTIVE: How variations of treatment time affect the safety and efficacy of Gamma Knife (GK) radiosurgery is a matter of considerable debate. With the relative simplicity of treatment planning for trigeminal neuralgia (TN), this question has been address ...

2020

Impact of the skull contour definition on Leksell Gamma Knife(R)Icon (TM) radiosurgery treatment planning

Constantin Tuleasca

Introduction The Gamma Knife(R)planning software (TMR 10, Elekta Instruments, AB, Sweden) affords two ways of defining the skull volume, the "historical" one using manual measurements (still perform in some centers) and the new one using image-based skull ...

2020

Automated computer-assisted quantitative analysis of intact murine lungs at the alveolar scale

Goran Lovric

Using state-of-the-art X-ray tomographic microscopy we can image lung tissue in three dimensions in intact animals down to a micrometer precision. The structural complexity and hierarchical branching scheme of the lung at this level of details, however, re ...

Public Library of Science2017

A multi-purpose imaging endstation for high-resolution micrometer-scaled sub-second tomography

Goran Lovric

Time-resolved imaging of dynamic processes, ranging from biological in vivo studies to materials under in situ and in operando conditions, requires a flexible endstation capable of controlling complex components that interact in different configurations an ...

Elsevier Sci Ltd2016

Prediction of transformation products during ozonation of micropollutant-containing waters : kinetics and mechanisms

Minju Lee

Ozonation, which is widely used for drinking water disinfection, has recently been applied to mitigate potentially harmful effects of micropollutants (e.g., pharmaceuticals, personal care products, pesticides, etc.) present in municipal wastewater effluent ...

EPFL2016

Optical microscopy for imaging through scattering media

Xin Yang

Optical microscopy has been widely used in the life sciences and biological research for several decades. It possesses many advantages over x-ray radiography, computed tomography, ultrasound imaging and magnetic resonance imaging, in terms of being low cos ...

EPFL2014

Proton-Radiation Tolerance of Silicon and SU-8 as Structural Materials for High-Reliability MEMS

Herbert Shea, Antonia Neels, Alex Dommann, Tobias Bandi

The susceptibility of single-crystal silicon and SU-8 resonators to proton-radiation induced degradation was investigated. Both materials are in widespread use for microsystems structures, thus the stability of the mechanical properties must be ensured ove ...

Institute of Electrical and Electronics Engineers2013

Low Doses of Ionizing Radiation Promote Tumor Growth and Metastasis by Enhancing Angiogenesis

Radiotherapy is a widely used treatment option in cancer. However, recent evidence suggests that doses of ionizing radiation (IR) delivered inside the tumor target volume, during fractionated radiotherapy, can promote tumor invasion and metastasis. Further ...

Public Library of Science2010

Simple dose rate measurements for a very high synchrotron X-ray flux

Giorgio Margaritondo

Dose measurements based on methylene blue (MB) bleaching, widely used for ultraviolet light, can also be applied to X-rays including very high flux levels. This method has been tested by using both MB bleaching and Fricke dosimetry for a conventional monoc ...

International Union of Crystallography2009

Predicting the bioavailability of metals and metal complexes: Critical review of the biotic ligand model

Environmental Context. The chemical speciation of trace metals greatly influences their biological effects. Nonetheless, no clear consensus currently exists as to when metal complexes are bioavailable, especially for field conditions. Recently, the USA EPA ...

2005