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Concept

Natural reservoir

Related publications (26)

Infection Dynamics and Immune Response in a Newly Described Drosophila-Trypanosomatid Association

Bruno Lemaitre, Anna Dostalova

Trypanosomatid parasites are significant causes of human disease and are ubiquitous in insects. Despite the importance of Drosophila melanogaster as a model of infection and immunity and a long awareness that trypanosomatid infection is common in the genus ...

American Society for Microbiology2015

Dynamics of HIV Latency and Reactivation in a Primary CD4+T Cell Model

Jacques Fellay, Christian Axel Wandall Thorball, Istvan Bartha

HIV latency is a major obstacle to curing infection. Current strategies to eradicate HIV aim at increasing transcription of the latent provirus. In the present study we observed that latently infected CD4+ T cells from HIV-infected individuals failed to pr ...

Public Library Science2014

Glucose- but Not Rice-Based Oral Rehydration Therapy Enhances the Production of Virulence Determinants in the Human Pathogen Vibrio cholerae

Andrea Rinaldo, Enrico Bertuzzo, Melanie Blokesch, Flavio Finger, Juliane Kühn

Despite major attempts to prevent cholera transmission, millions of people worldwide still must address this devastating disease. Cholera research has so far mainly focused on the causative agent, the bacterium Vibrio cholerae, or on disease treatment, but ...

2014

The Regulatory Network of Natural Competence and Transformation of Vibrio cholerae

Melanie Blokesch, Mirella Lo Scrudato

The human pathogen Vibrio cholerae is an aquatic bacterium frequently encountered in rivers, lakes, estuaries, and coastal regions. Within these environmental reservoirs, the bacterium is often found associated with zooplankton and more specifically with t ...

2012

On the role of human mobility in the spread of cholera epidemics: towards an epidemiological movement ecology

Andrea Rinaldo, Enrico Bertuzzo, Lorenzo Mari, Lorenzo Righetto

We investigate the role of human mobility as a driver for long-range spreading of cholera infections, which otherwise primarily propagate through hydrologically controlled ecological corridors. We rely on a recent mechanistic, field-data validated, spatial ...

Wiley-Blackwell2012

On the replication of adeno-associated virus in the presence or absence of viral helper functions

Adeno-associated virus (AAV) is a small non-enveloped virus and as a member of the parvovirus family, it contains a single stranded DNA genome. AAV's life cycle in vitro is strongly dependent not only on cellular factors but also on helper functions provid ...

EPFL2009