Paul Robert GuhennecMy research focuses on the usage of computational methods for architectural history and their epistemological implications. I am currently a post-doctoral researcher at EPFL's Digital Humanities Laboratory, where I recently finished my doctoral dissertation on Venice's urban and architectural history, entitled «The Skin of Venice: A Computational Approach to the City's Urban Structure».
Marcel SalathéTeaching & PhD PhD Students Laura Espinosa Montalbán, Marouane Toumi, Rohan Singh Past EPFL PhD Students Gianrocco Lazzari, Martin Mathias Müller, Sharada Prasanna Mohanty Courses Digital epidemiology BIO-512 Epidemiology is foundational to medicine and public health. This course starts with the key principles of classical epidemiology, progressing through computational modeling techniques, and concluding with the digital approaches of today. Students will also develop a digital epidemiolo
Henry MarkramHenry Markram started a dual scientific and medical career at the University of Cape Town, in South Africa. His scientific work in the 80s revealed the polymodal receptive fields of pontomedullary reticular formation neurons in vivo and how acetylcholine re-organized these sensory maps.
He moved to Israel in 1988 and obtained his PhD at the Weizmann Institute where he discovered a link between acetylcholine and memory mechanisms by being the first to show that acetylcholine modulates the NMDA receptor in vitro studies, and thereby gates which synapses can undergo synaptic plasticity. He was also the first to characterize the electrical and anatomical properties of the cholinergic neurons in the medial septum diagonal band.
He carried out a first postdoctoral study as a Fulbright Scholar at the NIH, on the biophysics of ion channels on synaptic vesicles using sub-fractionation methods to isolate synaptic vesicles and patch-clamp recordings to characterize the ion channels. He carried out a second postdoctoral study at the Max Planck Institute, as a Minerva Fellow, where he discovered that individual action potentials propagating back into dendrites also cause pulsed influx of Ca2 into the dendrites and found that sub-threshold activity could also activated a low threshold Ca2 channel. He developed a model to show how different types of electrical activities can divert Ca2 to activate different intracellular targets depending on the speed of Ca2 influx an insight that helps explain how Ca2 acts as a universal second messenger. His most well known discovery is that of the millisecond watershed to judge the relevance of communication between neurons marked by the back-propagating action potential. This phenomenon is now called Spike Timing Dependent Plasticity (STDP), which many laboratories around the world have subsequently found in multiple brain regions and many theoreticians have incorporated as a learning rule. At the Max-Planck he also started exploring the micro-anatomical and physiological principles of the different neurons of the neocortex and of the mono-synaptic connections that they form - the first step towards a systematic reverse engineering of the neocortical microcircuitry to derive the blue prints of the cortical column in a manner that would allow computer model reconstruction.
He received a tenure track position at the Weizmann Institute where he continued the reverse engineering studies and also discovered a number of core principles of the structural and functional organization such as differential signaling onto different neurons, models of dynamic synapses with Misha Tsodyks, the computational functions of dynamic synapses, and how GABAergic neurons map onto interneurons and pyramidal neurons. A major contribution during this period was his discovery of Redistribution of Synaptic Efficacy (RSE), where he showed that co-activation of neurons does not only alter synaptic strength, but also the dynamics of transmission. At the Weizmann, he also found the tabula rasa principle which governs the random structural connectivity between pyramidal neurons and a non-random functional connectivity due to target selection. Markram also developed a novel computation framework with Wolfgang Maass to account for the impact of multiple time constants in neurons and synapses on information processing called liquid computing or high entropy computing.
In 2002, he was appointed Full professor at the EPFL where he founded and directed the Brain Mind Institute. During this time Markram continued his reverse engineering approaches and developed a series of new technologies to allow large-scale multi-neuron patch-clamp studies. Markrams lab discovered a novel microcircuit plasticity phenomenon where connections are formed and eliminated in a Darwinian manner as apposed to where synapses are strengthening or weakened as found for LTP. This was the first demonstration that neural circuits are constantly being re-wired and excitation can boost the rate of re-wiring.
At the EPFL he also completed the much of the reverse engineering studies on the neocortical microcircuitry, revealing deeper insight into the circuit design and built databases of the blue-print of the cortical column. In 2005 he used these databases to launched the Blue Brain Project. The BBP used IBMs most advanced supercomputers to reconstruct a detailed computer model of the neocortical column composed of 10000 neurons, more than 340 different types of neurons distributed according to a layer-based recipe of composition and interconnected with 30 million synapses (6 different types) according to synaptic mapping recipes. The Blue Brain team built dozens of applications that now allow automated reconstruction, simulation, visualization, analysis and calibration of detailed microcircuits. This Proof of Concept completed, Markrams lab has now set the agenda towards whole brain and molecular modeling.
With an in depth understanding of the neocortical microcircuit, Markram set a path to determine how the neocortex changes in Autism. He found hyper-reactivity due to hyper-connectivity in the circuitry and hyper-plasticity due to hyper-NMDA expression. Similar findings in the Amygdala together with behavioral evidence that the animal model of autism expressed hyper-fear led to the novel theory of Autism called the Intense World Syndrome proposed by Henry and Kamila Markram. The Intense World Syndrome claims that the brain of an Autist is hyper-sensitive and hyper-plastic which renders the world painfully intense and the brain overly autonomous. The theory is acquiring rapid recognition and many new studies have extended the findings to other brain regions and to other models of autism.
Markram aims to eventually build detailed computer models of brains of mammals to pioneer simulation-based research in the neuroscience which could serve to aggregate, integrate, unify and validate our knowledge of the brain and to use such a facility as a new tool to explore the emergence of intelligence and higher cognitive functions in the brain, and explore hypotheses of diseases as well as treatments.
Guillaume AnciauxResearchResearch Topics My research can be decomposed in three main blocks:First, the main goal of my current research is the physical description of contact interactions. I performed numerous studies of this topic using different models from the continuum scale down to atomistic scale. Since atomic phenomena and macroscopic observations are linked, the physics of contact needs the simultaneous consideration of several scales. For instance, plasticity is a theory defined for the macroscopic scale whereas t
Linda MarchandTeaching & PhD Courses Applied statistics MATH-516 The course will provide an overview of everyday challenges in applied statistics through case studies. Students will learn how to use core statistical methods and their extensions, and will use computational and problem-solving tools to provide reproducible solutions for the problems presented. Bioinformatic Analysis of RNA-sequencing (Fall) BIO-693(a) Bioinformatic Analysis of RNA-sequencing (Spring) BIO-693(b)
Simone DeparisExpertise
Simone Deparis is a professor at EPFL specializing in applied mathematics, numerical analysis, and the didactics of university-level mathematics. His research spans computational modeling for biomedical applications and innovations in mathematics education, with a focus on equity, self-efficacy, and assessment reform in large STEM cohorts.
Mission
Our group conducts research at the intersection of applied mathematics and learning sciences. In applied mathematics, we focus on modeling and simulatio
Michaël UnserExpertise
Image Processing, Medical Imaging, Biological Imaging, Wavelets, Splines, Multiresolution
Michael Unser is Full Professor with EPFL’s school of Engineering and the academic director of EPFL's Center for Imaging, Lausanne, Switzerland. His primary areas of investigation are signal processing, biomedical imaging and applied functional analysis. He is internationally recognized for his research contributions to sampling theory, wavelets, the use of splines for image processing, stochastic processes,
Anne-Florence Raphaëlle BitbolI was trained in physics, and always had a strong interest in biology. I am broadly interested in understanding biological phenomena in a quantitative way, through physical concepts and mathematical and computational tools. I investigate the relative impacts of optimization and historical contingency in biological evolution, both at the scale of protein sequences and at the scale of microbial populations.Here is my research group website.Curriculum vitae Here is my complete CV. Professional experience:Since
Andrew James SontaExpertise
Human-building interaction, building energy, occupant behavior, sustainable design and planning, walkability, network analysis, machine learning, urban informatics, social systems.
Andrew Sonta is a tenure track assistant professor of sustainable civil engineering at EPFL. He directs the ETHOS Lab: Engineering and Technology for Human Oriented Sustainability. ETHOS is an interdisciplinary research group focused on using data-driven and computational tools to create interventions in the built envir
Wulfram GerstnerWulfram Gerstner is Director of the Laboratory of Computational Neuroscience LCN at the EPFL. His research in computational neuroscience concentrates on models of spiking neurons and spike-timing dependent plasticity, on the problem of neuronal coding in single neurons and populations, as well as on the link between biologically plausible learning rules and behavioral manifestations of learning. He teaches courses for Physicists, Computer Scientists, Mathematicians, and Life Scientists at the EPFL. After studies of Physics in Tübingen and at the Ludwig-Maximilians-University Munich (Master 1989), Wulfram Gerstner spent a year as a visiting researcher in Berkeley. He received his PhD in theoretical physics from the Technical University Munich in 1993 with a thesis on associative memory and dynamics in networks of spiking neurons. After short postdoctoral stays at Brandeis University and the Technical University of Munich, he joined the EPFL in 1996 as assistant professor. Promoted to Associate Professor with tenure in February 2001, he is since August 2006 a full professor with double appointment in the School of Computer and Communication Sciences and the School of Life Sciences. Wulfram Gerstner has been invited speaker at numerous international conferences and workshops. He has served on the editorial board of the Journal of Neuroscience, Network: Computation in Neural Systems', Journal of Computational Neuroscience', and `Science'.
Hervé BourlardTeaching & PhD Past EPFL PhD Students Astrid Hagen, Katrin Weber, Todd Stephenson, Jitendra Ajmera, Shajith Ikbal, Mathew Magimai Doss, Mohamed Faouzi Benzeghiba, Mark Barnard, Yann Rodriguez, Hemant Misra, Christos Dimitrakakis, Guillaume Lathoud, Alexei Pozdnoukhov, Agnès Just, Mikaela Keller, Norman Hoon Thian Poh, Dong Zhang, Florent Monay Michaud, Pedro Manuel Da Silva Quelhas, Kevin Smith, Silèye Oumar Ba, Bertrand Mesot, Hamed Ketabdar, David Grangier, Guillermo Aradilla, Jean-François Paiement, Nico
Samy BengioExpertise
Large Language ModelsReasoningStatistical machine learningSpeech processingPerson authenticationMultimodal processingSequence processingArtificial neural networks, support vector machinesHidden markov models, gaussian mixture modelsetc
Expertise
Large Language ModelsReasoningStatistical machine learningSpeech processingPerson authenticationMultimodal processingSequence processingArtificial neural networks, support vector machinesHidden markov models, gaussian mixture modelsetc
Mission
Samy Bengio
Laurence DanguyExpertise
History of European Art, 19th–21st CenturiesCultural History, 19th–21st Centuries
Laurence Danguy studied art history, history and archaeology at the University of Paris IV-Sorbonne and at the École des Hautes Études en Sciences Sociales (EHESS). She also studied management sciences at the University of Paris I-Panthéon-Sorbonne (MBA – IAE Paris). In 2006, she completed her PhD in History and Art Sciences as part of a joint supervision arrangement between the EHESS and the University of Konstanz (
Drazen DujicDrazen Dujic is an Associate Professor and Head of the Power Electronics Laboratory at EPFL. He received the Dipl.Ing. and MSc degrees from the University of Novi Sad, Serbia in 2002 and 2005, respectively, and the PhD degree from Liverpool John Moores University, UK in 2008. From 2003 to 2006, he was a Research Assistant with the Faculty of Technical Sciences at University of Novi Sad. From 2006 to 2009, he was a Research Associate with Liverpool John Moores University. After that he moved to industry and joined ABB Switzerland Ltd, where from 2009 to 2013, he was Scientist and then Principal Scientist with ABB Corporate Research Center in Baden-Dättwil, and from 2013 to 2014 he was R&D Platform Manager with ABB Medium Voltage Drives in Turgi. He joined EPFL in 2014 as Tenure Track Assistant Professor and was promoted to Associate Professor in 2021. His research interests include the areas of design and control of advanced high power electronic systems and high-performance drives, predominantly for the medium voltage applications related to electrical energy generation, conversion and storage. He has authored or coauthored more than 150 scientific publications and has filed 16 patents. In 2018 he received EPE Outstanding Service Award from European Power Electronics and Drives Association and in 2014 the Isao Takahashi Power Electronics Award for Outstanding Achievement in Power Electronics. He is Senior Member of IEEE, and serves as Associate Editor for IEEE Transactions on Power Electronics, IEEE Transactions on Industrial Electronics and IET Electric Power Applications. He is Chairman of the Swiss IEEE Power Electronics Society (PELS) Chapter and IEEE PELS R8 Chair.
Touradj EbrahimiTouradj EBRAHIMI received his M.Sc. and Ph.D., both in Electrical Engineering, from the Swiss Federal Institute of Technology (EPFL), Lausanne, Switzerland, in 1989 and 1992 respectively. In 1993, he was a research engineer at the Corporate Research Laboratories of Sony Corporation in Tokyo, where he conducted research on advanced video compression techniques for storage applications. In 1994, he served as a research consultant at AT&T Bell Laboratories working on very low bitrate video coding. He is currently Professor at EPFL heading its Multimedia Signal Processing Group. He is also the Convenor of JPEG standardization Committee. He was also adjunct Professor with the Center of Quantifiable Quality of Service at Norwegian University of Science and Technology (NTNU)from 2008 to 2012.
Prof. Ebrahimi has been the recipient of various distinctions and awards, such as the IEEE and Swiss national ASE award, the SNF-PROFILE grant for advanced researchers, Four ISO-Certificates for key contributions to MPEG-4 and JPEG 2000, and the best paper award of IEEE Trans. on Consumer Electronics . He became a Fellow of the international society for optical engineering (SPIE) in 2003. Prof. Ebrahimi has initiated more than two dozen National, European and International cooperation projects with leading companies and research institutes around the world. He is a co-founder of Genista SA, a high-tech start-up company in the field of multimedia quality metrics. In 2002, he founded Emitall SA, start-up active in the area of media security and surveillance. In 2005, he founded EMITALL Surveillance SA, a start-up active in the field of privacy and protection. He is or has been associate Editor with various IEEE, SPIE, and EURASIP journals, such as IEEE Signal Processing Magazine, IEEE Trans. on Image Processing, IEEE Trans. on Multimedia, EURASIP Image Communication Journal, EURASIP Journal of Applied Signal Processing, SPIE Optical Engineering Magazine. Prof. Ebrahimi is a member of Scientific Advisory Board of various start-up and established companies in the general field of Information Technology. He has served as Scientific Expert and Evaluator for Research Funding Agencies such as those of European Commission, The Greek Ministry of Development, The Austrian National Foundation for Scientific Research, The Portuguese Science Foundation, as well as a number of Venture Capital Companies active in the field of Information Technologies and Communication Systems. His research interests include still, moving, and 3D image processing and coding, visual information security (rights protection, watermarking, authentication, data integrity, steganography), new media, and human computer interfaces (smart vision, brain computer interface).
He is the author or the co-author of more than 200 research publications, and holds 14 patents. Prof. Ebrahimi is a member of IEEE, SPIE, ACM and IS&T.
See the URL below for more details:
http://mmspl.epfl.ch Pierre VandergheynstPierre Vandergheynst received the M.S. degree in physics and the Ph.D. degree in mathematical physics from the Université catholique de Louvain, Louvain-la-Neuve, Belgium, in 1995 and 1998, respectively. From 1998 to 2001, he was a Postdoctoral Researcher with the Signal Processing Laboratory, Swiss Federal Institute of Technology (EPFL), Lausanne, Switzerland. He was Assistant Professor at EPFL (2002-2007), where he is now a Full Professor of Electrical Engineering and, by courtesy, of Computer and Communication Sciences. As of 2015, Prof. Vandergheynst serves as EPFL’s Vice-Provost for Education. His research focuses on harmonic analysis, sparse approximations and mathematical data processing in general with applications covering signal, image and high dimensional data processing, computer vision, machine learning, data science and graph-based data processing. He was co-Editor-in-Chief of Signal Processing (2002-2006), Associate Editor of the IEEE Transactions on Signal Processing (2007-2011), the flagship journal of the signal processing community and currently serves as Associate Editor of Computer Vision and Image Understanding and SIAM Imaging Sciences. He has been on the Technical Committee of various conferences, serves on the steering committee of the SPARS workshop and was co-General Chairman of the EUSIPCO 2008 conference. Pierre Vandergheynst is the author or co-author of more than 70 journal papers, one monograph and several book chapters. He has received two IEEE best paper awards. Professor Vandergheynst is a laureate of the Apple 2007 ARTS award and of the 2009-2010 De Boelpaepe prize of the Royal Academy of Sciences of Belgium.
Anastasios VassilopoulosPERSONAL INFORMATION Name : Anastasios P. Vassilopoulos email : anastasios.vassilopoulos@epfl.ch Tel: 41 21 6936393 Fax: 41 21 6936240 SUMMARY OF QUALIFICATIONS 1995: Dipl. Mechanical Engineer, University of Patras, Greece 2001: Dr Mechanical Engineer, Doctoral thesis in fatigue of composite materials from the Dept. Mechanical Engineering and Aeronautics, University of Patras, Greece CURRENT POSITION Senior Scientist (MER), Composite Construction Laboaratory (CCLab), EPFL PREVIOUS POSITIONS 2006-2012 Research and Teaching Associate, Composite Construction Laboaratory (CCLab), EPFL 2002-2006 Assisstant Professor, Technological Educational Institute (TEI) of Patras, Greece 2001-2003 Post-doctoral Research associate, (Part-time) Dept. Mechanical Engineering and Aeronautics of the University of Patras, Greece. EDUCATION 1990 - 1995 Graduate student, Dept. Mechanical Engineering and Aeronautics, University of Patras, Greece October 1994-January 1995 Dept. Mechanical Engineering, University of Bristol, U.K. (In the frame of Erasmus project for the final year thesis, under the supervision of Prof. R. D. Adams) 1995 - 2000 Research assistant, Dept. Mechanical Engineering and Aeronautics, University of Patras. LANGUAGES English, Greek, French COMMUNITY ACTIVITIES (Member of) Council of the European Society of Composite Materials (ESCM) Council of the European Society of Experimental Mechanics (EuraSEM) The European Structural Integrity Society (ESIS) The European Energy Research Alliance (EERA, JP WIND) The Technical Chamber of Greece (TCG) The Hellenic Association of Mechanical & Electrical Engineers SCIENTIFIC-RESEARCH INTERESTS Experimental methods for the study of the behavior of composite materials under static and fatigue loading Development of analytical methods for the study of the behavior of FRP composite materials under variable amplitude complex stress states Development of fatigue life prediction methodologies for composite materials and structures Design of constructions with composite materials 