Francisella tularensis

Intracellular bacteria engage a STING-TBK1-MVB12b pathway to enable paracrine cGAS-STING signalling

Andrea Ablasser, Bing Zhang, Thomas Charles Henry Rossi

The innate immune system is crucial for eventual control of infections, but may also contribute to pathology. Listeria monocytogenes is an intracellular Gram-positive bacteria and a major cause of food-borne disease. However, important knowledge on the int ...

NATURE PUBLISHING GROUP2019

Using NanoSIMS coupled with microfluidics to visualize the early stages of coral infection by Vibrio coralliilyticus

Anders Meibom, Isabelle Domart-Coulon, Emma Mary Gibbin

Background: Global warming has triggered an increase in the prevalence and severity of coral disease, yet little is known about coral/pathogen interactions in the early stages of infection. The point of entry of the pathogen and the route that they take on ...

2018

An intracellular replication niche for Vibrio cholerae in the amoeba Acanthamoeba castellanii

Melanie Blokesch, Catherine Maclachlan, Charles Ulric V Van der Henst

Vibrio cholerae is a human pathogen and the causative agent of cholera. The persistence of this bacterium in aquatic environments is a key epidemiological concern, as cholera is transmitted through contaminated water. Predatory protists, such as amoebae, a ...

Nature Publishing Group2015

The Brucella pathogens are polarized bacteria

Charles Ulric V Van der Henst

Brucella pathogens are responsible for brucellosis, a worldwide zoonosis. They are facultative intracellular pathogens characterized by their asymmetric division and their unipolar growth. This growth modality generates poles with specialized functions (th ...

Elsevier Science Bv2013