Publications related to Hyperacusis

Functional MRI Neurofeedback Outperforms Cognitive Behavioral Therapy for Reducing Tinnitus Distress: A Prospective Randomized Clinical Trial

Dimitri Nestor Alice Van De Ville, Nicolas Gninenko

Background: Cognitive behavioral therapy (CBT) is the current standard treatment for chronic severe tinnitus; however, preliminary evidence suggests that real-time functional MRI (fMRI) neurofeedback therapy may be more effective. Purpose: To compare the e ...

Radiological Soc North America (Rsna)2024

Daily Contributors of Tinnitus Loudness and Distress: An Ecological Momentary Assessment Study

Patrick Karl Alois Neff

BackgroundTinnitus is a heterogeneous condition which may be associated with moderate to severe disability, but the reasons why only a subset of individuals is burdened by the condition are not fully clear. Ecological momentary assessment (EMA) allows a be ...

FRONTIERS MEDIA SA2022

Lower glutamate and GABA levels in auditory cortex of tinnitus patients: a 2D-JPRESS MR spectroscopy study

Thorsten Kleinjung, Patrick Karl Alois Neff

We performed magnetic resonance spectroscopy (MRS) on healthy individuals with tinnitus and no hearing loss (n = 16) vs. a matched control group (n = 17) to further elucidate the role of excitatory and inhibitory neurotransmitters in tinnitus. Two-dimensio ...

Nature Research2022

Negative Associations of Stress and Anxiety Levels With Cytotoxic and Regulatory Natural Killer Cell Frequency in Chronic Tinnitus

Patrick Karl Alois Neff

BackgroundDepression and anxiety are known to be associated with stress-induced changes in the immune system. Bothersome tinnitus can be related to stress and often co-occurs with depression and anxiety. This study investigates associations of psychologica ...

Frontiers Media2022

Circadian Regulation of Cochlear Sensitivity to Noise by Circulating Glucocorticoids

Benjamin Dieter Weger, Frédéric Bruno Martin Gachon

The cochlea possesses a robust circadian clock machinery that regulates auditory function. How the cochlear clock is influenced by the circadian system remains unknown. Here, we show that cochlear rhythms are system driven and require local Bmal1 as well a ...

2019

Gamma Knife radiosurgery for intravestibular and intracochlear schwannomas

Constantin Tuleasca

BackgroundSchwannomas of the VIIIth cranial nerve are benign tumours, with vast majority occurring in vestibular division. Rarely, they can also arise from distal branches of cochlear, superior or inferior vestibular. We review our experience with Gamma Kn ...

2019

Neuroimaging of human auditory cortex : data analysis and applications

Naghmeh Ghazaleh

Modern neuroimaging technologies provide us with non-invasive methods for study- ing structure and function, and plasticity of the human auditory cortex. Here we have acquired high spatial resolution functional magnetic resonance imaging (fMRI) data of the ...

EPFL2017

High-Resolution fMRI of Auditory Cortical Map Changes in Unilateral Hearing Loss and Tinnitus

Dimitri Nestor Alice Van De Ville, Wietske Van der Zwaag, Stephanie Clarke, Naghmeh Ghazaleh, Melissa Saenz

Animal models of hearing loss and tinnitus observe pathological neural activity in the tonotopic frequency maps of the primary auditory cortex. Here, we applied ultra high-field fMRI at 7 T to test whether human patients with unilateral hearing loss and ti ...

Springer Verlag2017

Investigations on the physical factors influencing the ear canal occlusion effect caused by hearing aids

Hervé Lissek, Thomas Stefan Zurbrügg

The occlusion effect refers to the altered perception of one's own voice when the ear canal is fully or partially obstructed. While the loudness increase due to body conducted sounds requires an assessment by psychoacoustic methods, the ratio of sound pres ...

Hirzel Verlag2014

Shunt loudspeakers for modal control in rooms

Hervé Lissek, Romain Boulandet, Pierre-Jean René

Engineers dealing with noise reduction in habitations close to transportation traffic or indus-trial facilities encounter several problems to decrease noise level in rooms at low frequencies. Passive materials and current building construction knowledge en ...

2009