Guido HaefeliTeaching & PhD PhD Students Federico Ronchetti, Gauri Napoletano Past EPFL PhD Students as codirector Axel Kuonen, Olivier Göran Girard, Carina Trippl Courses Particle detection PHYS-440 The course will cover the physics of particle detectors. It will introduce the experimental techniques used in nuclear and particle physics. The lecture includes the interaction of particles with matter, scintillators, gas detectors, silicon detectors, detectors for particle ID and photo-detectors.
Olivier SchneiderAfter his thesis defense in particle physics in 1989 at University of Lausanne, Olivier Schneider joins LBL, the Lawrence Berkeley Laboratory (California), to work on the CDF experiment at the Tevatron in Fermilab (Illinois), first as a research fellow supported by the Swiss National Science Foundation, and later as a post-doc at LBL. He participates in the construction and commissioning of the first silicon vertex detector to operate successfully at a hadron collider; this detector enabled the discovery of the sixth quark, named "top". Since 1994, he comes back to Europe and participates in the ALEPH experiment at CERN's Large Electron-Positron Collider, as CERN fellow and then as CERN scientific staff. He specializes in heavy flavour physics. In 1998, he becomes associate professor at University of Lausanne, then extraordinary professor at the Swiss Institute of Technology Lausanne (EPFL) in 2003, and finally full professor at EPFL in 2010. Having worked since 1997 on the preparation of the LHCb experiment at CERN's Large Hadron Collider, which started operation in 2009, he is now analyzing the first data. He also contributes since 2001 to the exploitation of the data recorded at the Belle experiment (KEK laboratory, Tsukuba, Japan). These two experiments study mainly the decays of hadrons containing a b quark, as well CP violation, i.e. the non-invariance under the symmetry between matter and antimatter.
David Atienza AlonsoDavid Atienza Alonso is an associate professor of EE and director of the Embedded Systems Laboratory (ESL) at EPFL, Switzerland. He received his MSc and PhD degrees in computer science and engineering from UCM, Spain, and IMEC, Belgium, in 2001 and 2005, respectively. His research interests include system-level design methodologies for multi-processor system-on-chip (MPSoC) servers and edge AI architectures. Dr. Atienza has co-authored more than 350 papers, one book, and 12 patents in these previous areas. He has also received several recognitions and award, among them, the ICCAD 10-Year Retrospective Most Influential Paper Award in 2020, Design Automation Conference (DAC) Under-40 Innovators Award in 2018, the IEEE TCCPS Mid-Career Award in 2018, an ERC Consolidator Grant in 2016, the IEEE CEDA Early Career Award in 2013, the ACM SIGDA Outstanding New Faculty Award in 2012, and a Faculty Award from Sun Labs at Oracle in 2011. He has also earned two best paper awards at the VLSI-SoC 2009 and CST-HPCS 2012 conference, and five best paper award nominations at the DAC 2013, DATE 2013, WEHA-HPCS 2010, ICCAD 2006, and DAC 2004 conferences. He serves or has served as associate editor of IEEE Trans. on Computers (TC), IEEE Design & Test of Computers (D&T), IEEE Trans. on CAD (T-CAD), IEEE Transactions on Sustainable Computing (T-SUSC), and Elsevier Integration. He was the Technical Program Chair of DATE 2015 and General Chair of DATE 2017. He served as President of IEEE CEDA in the period 2018-2019 and was GOLD member of the Board of Governors of IEEE CASS from 2010 to 2012. He is a Distinguished Member of ACM and an IEEE Fellow.
Michaël UnserExpertise
Image Processing, Medical Imaging, Biological Imaging, Wavelets, Splines, Multiresolution
Michael Unser is Full Professor with EPFL’s school of Engineering and the academic director of EPFL's Center for Imaging, Lausanne, Switzerland. His primary areas of investigation are signal processing, biomedical imaging and applied functional analysis. He is internationally recognized for his research contributions to sampling theory, wavelets, the use of splines for image processing, stochastic processes,
Lesya ShchutskaCurrent Work
Our research is focused on testing the boundaries of the Standard Model of particle physics and on looking for new phenomena which might explain unanswered puzzles in the fundamental description of the Universe. The examples of such puzzles would be dark matter nature, matter-antimatter asymmetry of the Universe or very small but non-zero neutrino masses.The main instrument for these tasks is the LHCb detector at CERN, where the analyses of the data collected in the LHC proton-proton collisions
Henry MarkramHenry Markram started a dual scientific and medical career at the University of Cape Town, in South Africa. His scientific work in the 80s revealed the polymodal receptive fields of pontomedullary reticular formation neurons in vivo and how acetylcholine re-organized these sensory maps.
He moved to Israel in 1988 and obtained his PhD at the Weizmann Institute where he discovered a link between acetylcholine and memory mechanisms by being the first to show that acetylcholine modulates the NMDA receptor in vitro studies, and thereby gates which synapses can undergo synaptic plasticity. He was also the first to characterize the electrical and anatomical properties of the cholinergic neurons in the medial septum diagonal band.
He carried out a first postdoctoral study as a Fulbright Scholar at the NIH, on the biophysics of ion channels on synaptic vesicles using sub-fractionation methods to isolate synaptic vesicles and patch-clamp recordings to characterize the ion channels. He carried out a second postdoctoral study at the Max Planck Institute, as a Minerva Fellow, where he discovered that individual action potentials propagating back into dendrites also cause pulsed influx of Ca2 into the dendrites and found that sub-threshold activity could also activated a low threshold Ca2 channel. He developed a model to show how different types of electrical activities can divert Ca2 to activate different intracellular targets depending on the speed of Ca2 influx an insight that helps explain how Ca2 acts as a universal second messenger. His most well known discovery is that of the millisecond watershed to judge the relevance of communication between neurons marked by the back-propagating action potential. This phenomenon is now called Spike Timing Dependent Plasticity (STDP), which many laboratories around the world have subsequently found in multiple brain regions and many theoreticians have incorporated as a learning rule. At the Max-Planck he also started exploring the micro-anatomical and physiological principles of the different neurons of the neocortex and of the mono-synaptic connections that they form - the first step towards a systematic reverse engineering of the neocortical microcircuitry to derive the blue prints of the cortical column in a manner that would allow computer model reconstruction.
He received a tenure track position at the Weizmann Institute where he continued the reverse engineering studies and also discovered a number of core principles of the structural and functional organization such as differential signaling onto different neurons, models of dynamic synapses with Misha Tsodyks, the computational functions of dynamic synapses, and how GABAergic neurons map onto interneurons and pyramidal neurons. A major contribution during this period was his discovery of Redistribution of Synaptic Efficacy (RSE), where he showed that co-activation of neurons does not only alter synaptic strength, but also the dynamics of transmission. At the Weizmann, he also found the tabula rasa principle which governs the random structural connectivity between pyramidal neurons and a non-random functional connectivity due to target selection. Markram also developed a novel computation framework with Wolfgang Maass to account for the impact of multiple time constants in neurons and synapses on information processing called liquid computing or high entropy computing.
In 2002, he was appointed Full professor at the EPFL where he founded and directed the Brain Mind Institute. During this time Markram continued his reverse engineering approaches and developed a series of new technologies to allow large-scale multi-neuron patch-clamp studies. Markrams lab discovered a novel microcircuit plasticity phenomenon where connections are formed and eliminated in a Darwinian manner as apposed to where synapses are strengthening or weakened as found for LTP. This was the first demonstration that neural circuits are constantly being re-wired and excitation can boost the rate of re-wiring.
At the EPFL he also completed the much of the reverse engineering studies on the neocortical microcircuitry, revealing deeper insight into the circuit design and built databases of the blue-print of the cortical column. In 2005 he used these databases to launched the Blue Brain Project. The BBP used IBMs most advanced supercomputers to reconstruct a detailed computer model of the neocortical column composed of 10000 neurons, more than 340 different types of neurons distributed according to a layer-based recipe of composition and interconnected with 30 million synapses (6 different types) according to synaptic mapping recipes. The Blue Brain team built dozens of applications that now allow automated reconstruction, simulation, visualization, analysis and calibration of detailed microcircuits. This Proof of Concept completed, Markrams lab has now set the agenda towards whole brain and molecular modeling.
With an in depth understanding of the neocortical microcircuit, Markram set a path to determine how the neocortex changes in Autism. He found hyper-reactivity due to hyper-connectivity in the circuitry and hyper-plasticity due to hyper-NMDA expression. Similar findings in the Amygdala together with behavioral evidence that the animal model of autism expressed hyper-fear led to the novel theory of Autism called the Intense World Syndrome proposed by Henry and Kamila Markram. The Intense World Syndrome claims that the brain of an Autist is hyper-sensitive and hyper-plastic which renders the world painfully intense and the brain overly autonomous. The theory is acquiring rapid recognition and many new studies have extended the findings to other brain regions and to other models of autism.
Markram aims to eventually build detailed computer models of brains of mammals to pioneer simulation-based research in the neuroscience which could serve to aggregate, integrate, unify and validate our knowledge of the brain and to use such a facility as a new tool to explore the emergence of intelligence and higher cognitive functions in the brain, and explore hypotheses of diseases as well as treatments.
Rolf GruetterAwards:
1999 Young Investigator Award Plenary Lectureship
, International Society for Neurochemistry
2011 Fellow
, ESMRMB
2011 Teaching Award
, Section Sciences de la Vie, EPFL
Hervé BourlardTeaching & PhD Past EPFL PhD Students Astrid Hagen, Katrin Weber, Todd Stephenson, Jitendra Ajmera, Shajith Ikbal, Mathew Magimai Doss, Mohamed Faouzi Benzeghiba, Mark Barnard, Yann Rodriguez, Hemant Misra, Christos Dimitrakakis, Guillaume Lathoud, Alexei Pozdnoukhov, Agnès Just, Mikaela Keller, Norman Hoon Thian Poh, Dong Zhang, Florent Monay Michaud, Pedro Manuel Da Silva Quelhas, Kevin Smith, Silèye Oumar Ba, Bertrand Mesot, Hamed Ketabdar, David Grangier, Guillermo Aradilla, Jean-François Paiement, Nico
Jan Sickmann HesthavenProf. Hesthaven received an M.Sc. in computational physics from the Technical University of Denmark (DTU) in August 1991. During the studies, the last 6 months of 1989 was spend at JET, the european fusion laboratory in Culham, UK. Following graduation, he was awarded a 3 year fellowship to begin work towards a Ph.D. at Riso National Laboratory in the Department of Optics and Fluid Dynamics. During the 3 years of study, the academic year of 1993-1994 was spend in the Division of Applied Mathematics at Brown University and three 3 months during the summer of 1994 in Department of Mathematics and Statistics at University of New Mexico. In August 1995, he recieved a Ph.D. in Numerical Analysis from the Institute of Mathematical Modelling (DTU). Following graduation in August 1995, he was awarded an NSF Postdoctoral Fellowship in Advanced Scientific Computing and was approinted Visiting Assistant Professor in the Division of Applied Mathematics at Brown University. In December of 1996, he was appointed consultant to the Institute of Computer Applications in Science and Engineering(ICASE) at NASA Langley Research Center (NASA LaRC). As of July 1999, he was appointed Assistant Professor of Applied Mathematics, in September 2000 he was awarded an Alfred P. Sloan Fellowship, as of July 2001 he was awarded a Manning Assistant Professorship, and in March 2002, he was awarded an NSF Career Award. In January 2003, he was promoted to Associate Professor of Applied Mathematics with tenure and in May 2004 he was awarded Philip J. Bray Award for Excellence in Teaching in the Sciences (the highest award given for teaching excellence in all sciences at Brown University). He was promoted to Professor of Applied Mathematics as of July 2005. From October 2006 to June 2013, he was the Founding Director of the Center for Computation and Visualization (CCV) at Brown University. As of October 2007, he holds the (honorary) title of Professor (Adjunct) at the Technical University of Denmark. In November 2009, he successfully defended his dr.techn thesis at the Technical University of Denmark and was rewarded the degree of Doctor Technices -- the highest academic distinction awarded based on ... substantial and lasting contributions that has helped to move the research area forward and penetrated into applications. As grant Co-PI he served from Aug 2010 to June 2013 as Deputy Director of the Institute of Computational and Experimental Research in Mathematics (ICERM), the newest NSF Mathematical Sciences Research Institute. After having spend his entire academic career at Brown University, Prof Hesthaven decided to pursue new challenges and joined the Mathematics Institute of Computational Science and Engineering (MATHICSE) at Ecole Polytechnique Fédérale de Lausanne (EPFL) in Switzerland in July 2013. In March 2014 he was elected SIAM Fellow for contributions to high-order methods for partial differential equations.
Pierre DillenbourgA former teacher in elementary school, Pierre Dillenbourg graduated in educational science (University of Mons, Belgium). He started his research on learning technologies in 1984. In 1986, he has been on of the first in the world to apply machine learning to develop a self-improving teaching system. He obtained a PhD in computer science from the University of Lancaster (UK), in the domain of artificial intelligence applications for education. He has been assistant professor at the University of Geneva. He joined EPFL in 2002. He has been the director of Center for Research and Support on Learning and its Technologies, then academic director of Center for Digital Education, which implements the MOOC strategy of EPFL (over 2 million registrations). He is full professor in learning technologies in the School of Computer & Communication Sciences, where he is the head of the CHILI Lab: "Computer-Human Interaction for Learning & Instruction ». He is the director of the leading house DUAL-T, which develops technologies for dual vocational education systems (carpenters, florists,...). With EPFL colleagues, he launched in 2017 the Swiss EdTech Collider, an incubator with 80 start-ups in learning technologies. He (co-)-founded 4 start-ups, does consulting missions in the corporate world and joined the board of several companies or institutions. In 2018, he co-founded LEARN, the EPFL Center of Learning Sciences that brings together the local initiatives in educational innovation. He is a fellow of the International Society for Learning Sciences. He currently is the Associate Vice-President for Education at EPFL.
