Ask any question about EPFL courses, lectures, exercises, research, news, etc. or try the example questions below.
DISCLAIMER: The Graph Chatbot is not programmed to provide explicit or categorical answers to your questions. Rather, it transforms your questions into API requests that are distributed across the various IT services officially administered by EPFL. Its purpose is solely to collect and recommend relevant references to content that you can explore to help you answer your questions.
Explores cellular senescence mechanisms induced by mitogenic signals, DNA damage, and oncogenes, emphasizing the role of key regulatory proteins and the impact on cell division.
Explores replicative immortality in cancer cells, focusing on telomere erosion, telomerase activity, and the role of p53 in maintaining genomic stability.
Covers mutations, classification, causes, and repair mechanisms of DNA, including spontaneous and induced mutations, replication errors, and DNA damage.
Explores DNA repair mechanisms, including BER, MMR, NER, and repair of double-strand breaks, as well as the impact of UV-induced lesions and resistance to PARP inhibitors.
Explores p53's pivotal role in cellular stability, DNA repair, and tumor suppression, emphasizing TP53 mutations and DNA double-strand break repair mechanisms.
Explores the applications of CRISPR-Cas in genome editing, focusing on engineering bacterial genomes, curing genetic diseases, guide RNA simplicity, Cas9 specificity, DNA damage mechanisms, and base editing.
Explores T and B lymphocyte maturation, receptor gene rearrangement, diversity generation, TCR structure, immunological synapse, and signaling pathways.
