Concept

Ranitidine

Drugbox |Verifiedfields = changed |Watchedfields = changed |verifiedrevid = 458460406 |image = Ranitidine.svg |width = 250 |image2 = File:Ranitidine-A-3D-balls.png |JAN = ranitidine hydrochloride |tradename = Zantac, others |Drugs.com = |MedlinePlus = a601106 |licence_CA = |licence_EU = |DailyMedID = Ranitidine |licence_US = Ranitidine |pregnancy_AU = B1 |pregnancy_AU_comment = |routes_of_administration = By mouth, intravenous (IV) |class = Histamine H2 receptor antagonist, aka H2 blocker |ATC_prefix = A02 |ATC_suffix = BA02 |ATC_supplemental = (ranitidine bismuth citrate) |legal_AU = S4 |legal_AU_comment = / S2 (Pharmacy Medicine) |legal_BR = |legal_CA = |legal_DE = |legal_NZ = |legal_UK = POM |legal_UK_comment = / GSL (General sales list) |legal_US = Rx-only |legal_US_comment = / OTC |legal_EU = Rx-only |legal_UN = |bioavailability = 50% (by mouth) |protein_bound = 15% |metabolism = Liver: FMOs, including FMO3; other enzymes |onset = 55–65 minutes (150 mg dose)55–115 minutes (75 mg dose) |elimination_half-life = 2–3 hours |duration_of_action = |excretion = 30–70% kidney |index2_label = HCl |CAS_number_Ref = |CAS_number = 66357-35-5 |CAS_number2_Ref = |CAS_number2 = 66357-59-3 |PubChem = 3001055 |PubChem2 = 3033332 |IUPHAR_ligand = 1234 |DrugBank_Ref = |DrugBank = DB00863 |DrugBank2_Ref = |DrugBank2 = DBSALT000487 |ChemSpiderID_Ref = |ChemSpiderID = 4863 |ChemSpiderID2_Ref = |ChemSpiderID2 = 43590 |UNII_Ref = |UNII = 884KT10YB7 |UNII2_Ref = |UNII2 = BK76465IHM |KEGG_Ref = |KEGG = D00422 |KEGG2_Ref = |KEGG2 = D00673 |ChEBI_Ref = |ChEBI = 8776 |ChEBI2_Ref = |ChEBI2 = 8777 |ChEMBL_Ref = |ChEMBL = 1790041 |ChEMBL2_Ref = |ChEMBL2 = 2110372 |synonyms = Dimethyl [(5-{[(2-{[1-(methylamino)-2-nitroethenyl]amino}ethyl)sulfanyl]methyl}furan-2-yl)methyl]amine |IUPAC_name = N-(2-[(5-[(Dimethylamino)methyl]furan-2-yl)methylthio]ethyl)-''N-methyl-2-nitroethene-1,1-diamine |C = 13 | H = 22 | N = 4 | O = 3 | S = 1 |SMILES = CNC(=CN+[O-])NCCSCC1=CC=C(O1)CN(C)C |StdInChI_Ref = |StdInChI = 1S/C13H22N4O3S/c1-14-13(9-17(18)19)15-6-7-21-10-12-5-4-11(20-12)8-16(2)3/h4-5,9,14-15H,6-8,10H2,1-3H3 |StdInChIKey_Ref = |StdInChIKey = VMXUWOKSQNHOCA-UHFFFAOYSA-N Ranitidine, sold under the brand name Zantac among others, is a medication used to decrease stomach acid production.

Official source

https://en.wikipedia.org/wiki/Ranitidine

About this result

This page is automatically generated and may contain information that is not correct, complete, up-to-date, or relevant to your search query. The same applies to every other page on this website. Please make sure to verify the information with EPFL's official sources.

Related publications (2)

Model-based meta-analysis of individual patient data for the characterization of intravenous 5-fluorouracil population pharmacokinetics

Purpose: The pharmacokinetics (PK) of 5-fluorouracil (5-FU) has been thoroughly studied over the past decades. Using an individual patient data model-based meta-analysis (IPD-MBMA) approach, this study aims to build a generalized model by combining IPD from multiple studies, investigating the role of lean body mass (LBM) in 5-FU PK, and exploring a model informed precision dosing (MIPD)-based approach for refining its therapeutic drug monitoring (TDM). Methods: Raw PK data from three 5-FU PK studies (726 p

Springer Science and Business Media LLC2026

Data-Driven Approaches Applied to Electrochemical Measurements for Therapeutic Drug Monitoring in Precision Medicine

Precision medicine increasingly relies on therapeutic drug monitoring (TDM) to individualize dosing and improve clinical outcomes. By integrating pharmacokinetic models with patient-specific observations, model-informed precision dosing (MIPD) enables quantitative dose adaptation based on measured drug concentrations. However, conventional laboratory-based TDM workflows are often slow, resource-intensive, and poorly suited for rapid clinical decision-making. In contrast, emerging point-of-care (POC) electro

EPFL2026

Related people (2)

Florian Frédéric Vincent Breider

Florian Breider obtained his PhD in the field of the stable isotope biogeochemistry from the University of Neuchatel in 2013. This was followed by seven months of postdoc at EPFL in the Atmospheric Particles Research Laboratory and two years as research associate at Tokyo Institute of Technology (Japan) where he conducted studies on nitrous oxide biogeochemistry in oceans. From 2015 to 2018, he was research scientist in the Laboratory for Water Quality and Treatment at EPFL where he conducted research on disinfection by-products and antibiotic resistant bacteria. Since May 2018, he is director of the Central Environmental Laboratory at the Institute of Environmental Engineering of EPFL.

Minju Lee

Graph Chat

Chat with Graph Search

Ask any question about EPFL courses, lectures, exercises, research, news, etc. or try the example questions below.

DISCLAIMER: The Graph Chatbot is not programmed to provide explicit or categorical answers to your questions. Rather, it transforms your questions into API requests that are distributed across the various IT services officially administered by EPFL. Its purpose is solely to collect and recommend relevant references to content that you can explore to help you answer your questions.

Official source

https://en.wikipedia.org/wiki/Ranitidine

About this result

Related publications (2)

Model-based meta-analysis of individual patient data for the characterization of intravenous 5-fluorouracil population pharmacokinetics

Springer Science and Business Media LLC2026

Data-Driven Approaches Applied to Electrochemical Measurements for Therapeutic Drug Monitoring in Precision Medicine

EPFL2026

Related people (2)

Florian Frédéric Vincent Breider

Minju Lee

Related concepts (9)

Vitamin B12

Vitamin B12, also known as cobalamin, is a water-soluble vitamin involved in metabolism. It is one of eight B vitamins. It is required by animals, which use it as a cofactor in DNA synthesis, and in both fatty acid and amino acid metabolism. It is important in the normal functioning of the nervous system via its role in the synthesis of myelin, and in the circulatory system in the maturation of red blood cells in the bone marrow. Plants do not need cobalamin and carry out the reactions with enzymes that are not dependent on it.

H2 receptor antagonist

DISPLAYTITLE:H2 receptor antagonist H2 antagonists, sometimes referred to as H2RAs and also called H2 blockers, are a class of medications that block the action of histamine at the histamine H2 receptors of the parietal cells in the stomach. This decreases the production of stomach acid. H2 antagonists can be used in the treatment of dyspepsia, peptic ulcers and gastroesophageal reflux disease.

Diclofenac

Diclofenac, sold under the brand name Voltaren, among others, is a nonsteroidal anti-inflammatory drug (NSAID) used to treat pain and inflammatory diseases such as gout. It is taken by mouth or rectally in a suppository, used by injection, or applied to the skin. Improvements in pain last for as much as eight hours. It is also available in combination with misoprostol in an effort to decrease stomach problems. Common side effects include abdominal pain, gastrointestinal bleeding, nausea, dizziness, headache, and swelling.