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Concept

Molecular switch

Related publications (29)

Photochromic Torsional Switch (PTS): a Light-Driven Actuator for the Dynamic Tuning of π-Conjugation Extension

Anne-Clémence Corminboeuf, Pascal Miéville, Riccardo Petraglia, Giuseppe Sforazzini, Emilie Baudat, Adrien Georges Nicolai, Adam Antoni Sobczuk

Here we present a molecular architecture that can reversibly change the geometric conformation of its π-system backbone via irradiation with two different wavelengths. The proposed ‘molecular actuator’ consists of a photoswitchable azobenzene orthogonally ...

2016

Mechanistic Studies on the Stereoselectivity of the Serotonin 5-HT1A Receptor

Horst Arthur Vogel, Shuguang Yuan

G-protein-coupled receptors (GPCRs) are involved in a wide range of physiological processes, and they have attracted considerable attention as important targets for developing new medicines. A central and largely unresolved question in drug discovery, whic ...

Wiley-Blackwell2016

Crystalline and Soft Materials Based on Dative Boron-Nitrogen Bonds

Nicolas Luisier

The thesis describes the utilization of dative boron-nitrogen bond is used for the construction of new materials. In chapter 2.1, the synthesis of new organogels based on bisimidazolyl ligands and diboronate esters is described. Gels with a critical gel co ...

EPFL2016

High aspect ratio nanofibril materials

Jeffrey Alan Hubbell

The present invention features linear and three-dimensional supramolecular materials self-assembled from block copolymers comprising oligo(ethylene sulfide) (OES). The block copolymers assemble into fibrils, micelles, or matrices. The fibrillar materials a ...

2015

TiO2 Anatase with a Bandgap in the Visible Region

Klaus Kern, Feliciano Giustino, Christopher Seiji Kley, Christian Alexander Stephan Dette

TiO2 anatase plays a central role in energy and environmental research. A major bottleneck toward developing artificial photosynthesis with TiO2 is that it only absorbs ultraviolet light, owing to its large bandgap of 3.2 eV. If one could reduce the bandga ...

Amer Chemical Soc2014

Dual and multi-stimuli responsive polymeric nanoparticles for programmed site-specific drug delivery

Harm-Anton Klok

In the past decades, polymeric nanoparticles have emerged as a most promising and viable technology platform for targeted and controlled drug delivery. As vehicles, ideal nanoparticles are obliged to possess high drug loading levels, deliver drug to the sp ...

Elsevier Sci Ltd2013

Conductance Switching and Many-Valued Logic in Porphyrin Assemblies

Nicola Marzari

We investigate quantum interference in the transport properties of porphyrin-based molecular devices, and are able to develop a minimal but qualitatively accurate model of conductance based on the maximally localized Wannier functions of just the isolated ...

Amer Chemical Soc2013

Encapsulation of inorganic and organic guest molecules into an organometallic hexacationic arene osmium metalla-prism: Synthesis, characterisation and anticancer activity

Paul Joseph Dyson, Olivier Pierre Zava

The arene osmium metalla-prism (p-cymene)(6)Os-6(donq)(3)(tpt)(2) (2) (donq 5,8-dioxydo-1,4-naphthoquinonato, tpt 2,4,6-tri(pyridin-4-yl)-1,3,5-triazine) has been prepared from the dinuclear arene osmium precursor [(p-cymene)(2)Os-2(donq)Cl-2] ...

Elsevier2012

Nanopore sensing of single molecules application to RNAP-DNA complexes, fabrication of graphene-nanopore devices and translocation algorithm analysis

Camille Alice Raillon

Nanopore sensing is a single-molecule technique that allows to probe the nano-bio-world with accuracy. It is a non-invasive technique, which means that the molecule of interest does not need to be labeled to be detected by the nanopore. Most of the studies ...

EPFL2012