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Concept

Frequency modulation synthesis

Related publications (23)

Discovery of macrocyclic inhibitors of challenging protein-protein interactions

Edward Jeffrey Will

Macrocycles are a therapeutic modality of interest for drugging challenging disease targets due to their high binding affinity and membrane permeability, enabling the discovery of orally delivered and efficacious therapeutics. Recent methods have enabled t ...

EPFL2024

A chip-scale second-harmonic source via self-injection-locked all-optical poling

Tobias Kippenberg, Camille Sophie Brès, Junqiu Liu, Edgars Nitiss, Marco Clementi

Second-harmonic generation allows for coherently bridging distant regions of the optical spectrum, with applications ranging from laser technology to self-referencing of frequency combs. However, accessing the nonlinear response of a medium typically requi ...

2023

Modular Synthesis of Benzocyclobutenes via Pd(II)-Catalyzed Oxidative [2+2] Annulation of Arylboronic Acids with Alkenes

Jieping Zhu, Anne-Clémence Corminboeuf, Qian Wang, Simone Gallarati, Takuji Fujii

Benzocyclobutenes (BCBs) are highly valuable compounds in organic synthesis, medicinal chemistry, and materials science. However, catalytic modular synthesis of functionalized BCBs from easily accessible starting materials remains limited. We report herein ...

2022

A Fully-Integrated 40-nm 5-6.5 GHz Cryo-CMOS System-on-Chip with I/Q Receiver and Frequency Synthesizer for Scalable Multiplexed Readout of Quantum Dots

Edoardo Charbon, Andrea Ruffino, Yatao Peng

Quantum computing holds the promise to solve many of today's intractable problems. A solid-state quantum computer (QC) is generally made of an array of qubits implemented in one of many solid-state technologies and operating at deep-cryogenic temperatures ...

IEEE2021

Methods to Enhance Nuclear Magnetic Resonance Sensitivity at High Magnetic Field

Claudia Christina Zanella

MR is a well-established technique routinely used in preclinical and clinical studies. This thesis focussed on the improvement of sensitivity of different methods in MR. Hyperpolarized 129Xe gas is used for studying pulmonary disease or cerebral perfusion ...

EPFL2021

Synthetic Studies toward Amanita Phalloides Toxins

Philipp Georg Werner Seeberger

Amatoxins are ribosomally synthesized and post-translationally modified bicyclic octapeptides biosynthesized by the deadly basidiomycete fungus Amanita phalloides. Amongst this group, alpha-amanitin is the most widely known toxin and is currently under inv ...

EPFL2020

V-band nanosecond-scale pulse reflectometer diagnostic in the TCV tokamak

Stefano Coda, Laurie Porte, Pedro Andres Molina Cabrera

This article describes the realization of a novel approach to short pulse (∼1 ns) reflectometry (SPR) recently implemented in the tokamak configuration variable tokamak. Taking advantage of a fast arbitrary waveform generator and vector-network-analyzer ex ...

2019

Tokamak plasma edge studies by microwave short-pulse reflectometry and backscattering

Pedro Andres Molina Cabrera

Moving towards an increased understanding of the dynamic processes in the edge of tokamak plasmas requires continuous innovation in diagnostic capabilities, pushing the envelope in both spatial and temporal dimenstions. Plasma density and rotation, and the ...

EPFL2019

Localization of emergency acoustic sources by micro aerial vehicles

Dario Floreano, Felix Stephan Schill, Meysam Basiri

For micro aerial vehicles (MAVs) involved in search and rescue missions, the ability to locate the source of a distress sound signal is significantly important and allows fast localization of victims and rescuers during nighttime, through foliage and in du ...

John Wiley & Sons2017

20-300 MHz Frequency Generator with-70 dBc Reference Spur for Low Jitter Serial Applications

Catherine Dehollain, Gürkan Yilmaz

This paper presents a frequency synthesizer based on a phase locked loop (PLL) targeting low jitter applications. The frequency generator covers a range wider than a decade, more explicitly from 20 to 300 MHz. Thanks to a 4-stage ring oscillator, it can pr ...

Ieee2016

Ultra Low-Power Frequency Synthesizers for Duty Cycled IoT radios

Raghavasimhan Thirunarayanan

Internet of Things (IoT), which is one of the main talking points in the electronics industry today, consists of a number of highly miniaturized sensors and actuators which sense the physical environment around us and communicate that information to a cent ...

EPFL2016

High-level system synthesis and optimization of dataflow programs for MPSoCs

Marco Mattavelli, Simone Casale Brunet, Endri Bezati

The growing complexity of digital signal processing applications make a compelling case the use of high-level design and synthesis methodologies for the implementation on reconfigurable and embedded devices. Past research has shown that raising the level o ...

2016

High-level synthesis of dynamic dataflow programs on heterogeneous MPSoC platforms

Marco Mattavelli, Simone Casale Brunet, Endri Bezati

The growing complexity of digital signal processing applications make a compelling case the use of high-level design and synthesis methodologies for the implementation on programmable logic devices and embedded processors. Past research has shown that, for ...

2016

On-chip synthesis of fine-tuned bone-seeking hybrid nanoparticles

Philippe Renaud, Arnaud Bertsch, Mohammad Mahdi Hasani-Sadrabadi

Aims: Here we report a one-step approach for reproducible synthesis of finely tuned targeting multifunctional hybrid nanoparticles (HNPs). Materials & methods: A microfluidic-assisted method was employed for controlled nanoprecipitation of bisphosphonate-c ...

Future Medicine Ltd2015

Fine DNA structure revealed by constant height frequency modulation AFM imaging

Giovanni Dietler, Dusan Vobornik, Andrea Cerreta

Few examples of sub nanometer resolution on biomolecules can be found in literature. In particular, AFM experiments on DNA mostly fail to show the double helical groove periodicity, and so far such a feat was only achieved in liquid. Here we describe a met ...

Elsevier2013

Source/Filter Factorial Hidden Markov Model, with Application to Pitch and Formant Tracking

Jean-Philippe Thiran

Tracking vocal tract formant frequencies (

f_p

) and estimating the fundamental frequency (

f_0

) are two tracking problems that have been tackled in many speech processing works, often independently, with applications to articulatory parameters estimation ...

Institute of Electrical and Electronics Engineers2013

Chiral Monodentate Trialkylphosphines Based on the Phospholane Architecture

Nicolai Cramer, Tanguy Jean Daniel Saget, Pavel Alexandrovich Donets

The development of efficient chiral monodentate phosphine ligands lags behind that of the bidentate congeners. This holds especially true for highly electron rich chiral phosphine analogues able to replace the ubiquitous tricyclohexylphosphine and tri-tert ...

Amer Chemical Soc2012

FM-AFM constant height imaging and force curves: high resolution study of DNA-tip interactions

Giovanni Dietler, Livan Bladimir Alonso Sarduy, Dusan Vobornik, Andrea Cerreta, Susana del Carmen Tobenas Borron

Interaction of the atomic force microscopy (AFM) tip with the sample can be invasive for soft samples. Frequency Modulation (FM) AFM is gentler because it allows scanning in the non-contact regime where only attractive forces exist between the tip and the ...

Wiley-Blackwell2012

Design of a 2.4 Ghz BAW-Based CMOS Transmitter

In recent years, bulk acoustic wave resonators (BAW) in combination with RF circuits have shown a big potential in achieving the low-power consumption and miniaturization level required to address wireless sensor nodes (WSN) applications. A lot of work has ...

EPFL2011

Autoregressive Models of Amplitude Modulations in Audio Compression

Petr Motlicek, Hynek Hermansky, Sriram Ganapathy

We present a scalable medium bit-rate wide-band audio coding technique based on frequency domain linear prediction (FDLP). FDLP is an efficient method for representing the long-term amplitude modulations of speech/audio signals using autoregressive models. ...

2010