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Drug discovery

Related lectures (32)

Pharmacodynamics: Ligand-Receptor Binding and Drug Effects

Explores ligand-receptor binding, drug effects, efficacy, potency, and biased agonism in pharmacodynamics.

Drug Discovery: Computational Approaches

Explores the EXSCALATE4COV project, focusing on computational drug discovery for COVID-19 treatments and the collaboration between academia and industry.

The ClpXP Proteolytic Complex: Basic Principles to Drug Discovery

Explores the ClpXP proteolytic complex, its drug targeting potential, and antimicrobial applications through compound screening.

Pharmacodynamics: Ligand-Receptor Interactions and Drug Effects

Explores ligand-receptor interactions, drug effects, modulation mechanisms, and factors influencing drug responses.

Pharmacodynamics: Ligand Concentration, Binding, and Effect

Explores the relationship between ligand concentration, binding, and effect, focusing on allosteric modulators and types of pharmacological antagonists.

DNA-Encoded Libraries

Explores DNA-encoded libraries for drug discovery, covering synthesis techniques, pros and cons, and diverse DEL methods.

Deep Generative Models in Drug Discovery

Explores the application of deep generative models in drug discovery, focusing on designing small molecules and optimizing molecular structures.

Kidney-on-a-Chip Technologies

Covers the state-of-the-art kidney-on-chip technologies aiming to facilitate pharmaceutical research and eliminate animal testing.

Pharmacodynamics exercises

Covers the analysis of binding measurements and toxin kinetics in pharmacodynamics.

Protein Engineering & In vitro Evolution

Explores protein engineering, screening methods, scaffold properties, computational design, and continuous evolution of biomolecules.

Predicting COVID-19 Therapeutic Mechanisms

Explores computational methods to predict COVID-19 therapeutic mechanisms through drug repurposing and machine learning.

Total Synthesis: Regidins and Ecteinascidin-743

Explores the total synthesis of Regidins and Ecteinascidin-743, along with the unique structure of (+)-Peganumine A.

Neurotransmitter Glutamate: Receptor Dynamics and Pharmacodynamics

Explores neurotransmitter dynamics, receptor interactions, and pharmacological concepts in CNS synapses.

Tissue Engineering for Cancer Research

Explores the complexity of cancer, challenges in research translation, and the applications of tissue engineering for cancer models and drug screening.

Pharmacodynamics: Ligand-Receptor Binding Kinetics

Explores ligand-receptor binding kinetics, concentration-effect relationship, and drug therapy impact.

Drug Target Discovery: Thermal Shift Profiling

Covers drug target discovery through stability shifts and proteomics with isobaric tags.

Pharmacodynamics: Quantitative Description of Ligand-Receptor Binding

Delves into the quantitative aspects of ligand-receptor binding and receptor occupancy.

Frontiers in Chemical Biology

Explores the druggable proteome, PROTACS strategy, ubiquitin attachment, and drug development paradigms.

Enantioselective C-H Activation

Explores enantioselective C-H activation reactions using Cu, Rh, and Ni catalysts for functionalization of olefins, alkynes, and alkenes.

Protein Engineering & In Vitro Evolution

Explores protein engineering, computational design, and screening protein libraries to generate novel proteins with desired functions.